Results 61 to 70 of about 70,000 (263)

Swollen Feet: Considering the Paradoxical Roles of Interleukins in Nephrotic Syndrome

Biomedicines
Interleukins are a family of 40 bioactive peptides that act through cell surface receptors to induce a variety of intracellular responses. While interleukins are most commonly associated with destructive, pro-inflammatory signaling in cells, some also ...
Maria E. Kovalik, Monique A. Dacanay, Steven D. Crowley, Gentzon Hall   +3 more
doaj   +1 more source

Serum Cytokine Profile in Patients with Candidemia versus Bacteremia

Pathogens, 2021
Bloodstream Candida infections constitute a major threat for hospitalized patients in intensive care units and immunocompromised hosts. Certain serum cytokines play a decisive role in anti-microbial host defense.
Saad J. Taj-Aldeen, Fayaz Ahmad Mir, Siveen K. Sivaraman, Atqah AbdulWahab   +3 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

The relationship between past coronavirus infection and the content of serum interleukins in diseases of the nervous system

Acta Biomedica Scientifica
Background. The mediators of inflammation, which is the most important mechanism for the development of coronavirus infection, accompanied by various complications from the nervous system, both in the acute period of the disease and in the long term, are
P. E. Borodin
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

The Relationship of Kidney Injury Molecule-1 and Interleukin-1 Beta with Hepatic and Renal Functions in Pregnant Women with Thyroid Disease

İstanbul Medical Journal, 2022
Introduction:Pregnancy is considered a low-grade inflammatory state presented with increased levels of pro-inflammatory markers. Despite the well-recognized association between inflammation and kidney injury, there is still a lack of available data ...
Emel Sağlam, Bennur Esen, Saadet Pilten, Vüsale Gözütok, Ahmet Engin Atay   +4 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Systemic interleukins levels in community-acquired pneumonia and their association with adverse outcomes

Romanian Journal of Laboratory Medicine, 2019
Introduction: Community-acquired pneumonia (CAP) is still one of the major causes of morbidity and mortality worldwide. Pro-inflammatory and anti-inflammatory interleukins have been studied to elucidate the role that inflammation plays in its ...
Tripon Raluca Elena, Neagoe Ioana Berindan, Budisan Livia, Pop Tudor Lucian, Cristea Victor, Stanca Liana Maria, Lupse Mihaela Sorina   +6 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Relationship between disorders of adipose tissue hormones and interleukins in patients with hypertension and comorbid pathology

Zaporožskij Medicinskij Žurnal, 2017
The purpose of research – was to improve the efficiency of diagnostics of arterial hypertension (AH) with comorbid disorders (diabetes mellitus (DM) and obesity) by studying hormones of adipose tissue (leptin and adiponectin) and the inflammatory markers
B. O. Shelest
doaj   +1 more source