Results 51 to 60 of about 80,628 (293)
Interleukin-17A and interleukin-23 in morphea
Archives of Medical Science, 2012 Morphea is a disease included in the group of scleroderma type autoimmune diseases. Interleukin (IL)-17A may play a role at every stage of its pathogenesis. The study aimed at evaluation of IL-17A and IL-23 (as the main cytokine which is supposed to stimulate and maintain synthesis of IL-17) in pathogenesis of morphea.The studies were performed on 41 ...
Dańczak-Pazdrowska, Aleksandra +9 more
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Zdorovʹe Rebenka, 2012 The analysis of interleukins content in children depending on the size of ulcerous defect, severity of inflammation, toxigenicity of Helicobacter pylori strains was carried out.
S.V. Sokolnyk
doaj +1 more source
Serum B cell activating factor and interleukin 10 levels in common variable immunodeficiency: Relationship with clinical findings [PDF]
Vojnosanitetski Pregled, 2019 Background/Aim. Common variable immunodeficiency (CVID) is an immunologically and clinically heterogeneous disorder. Disturbed cytokine production is implicated in dysfunctional immune response. The aim of this study was to investigated B-cell activating
Mijanović Radovan +3 more
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Vertebrate interleukins originated in invertebrates? [PDF]
Invertebrate Survival Journal, 2007 Previous studies have demonstrated that invertebrate immune and neural tissues contain mammalian-like cytokines, which activate specific cellular functions. Therefore, it was of interest to attempt to identify these molecules via Applied Biosystems Human
S Gerber +4 more
doaj +1 more source
Interleukin-1 and interleukin-1 antagonism [PDF]
Blood, 1991 The polypeptide cytokine interleukin-1 (IL-1) affects nearly every tissue and organ system. IL-1 is the prototype of the pro-inflammatory cytokines in that it induces the expression of a variety of genes and the synthesis of several proteins that, in turn, induce acute and chronic inflammatory changes.
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Frontiers in Immunology, 2020 Objective: Interleukin-15 (IL-15) is a pro-inflammatory cytokine that is increased in joint fluids of early-stage osteoarthritis (OA) patients, and has been associated with expression of proteases that can damage cartilage, and the development of ...
Sophie C. Warner +9 more
doaj +1 more source
СORONAVIRUS INFECTION WITH AN OBESITY
Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2021 Summary. Relevance of the topic: most of the world is obese and there are enough cases of the impact of this pathology on the development of a complicated and severe course of novel coronavirus (COVID-19)infection.
S. N. Ionov +4 more
doaj +1 more source
Interleukin-18: Perspectives on the Newest Interleukin
Cytokine & Growth Factor Reviews, 1998 Just over two years ago the newest member of the interleukin family of cytokines, IL-18, was molecularly cloned. IL-18 was originally identified as a result of its ability to induce interferon gamma production, however with the advent of its cloning and the production of recombinant protein a number of other biological actions have since been ...
Gillespie, M T, Horwood, N J
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source