Results 51 to 60 of about 70,247 (263)

Differential expression of IL-17, 22 and 23 in the progression of colorectal cancer in patients with K-ras mutation: Ras signal inhibition and crosstalk with GM-CSF and IFN-γ.

PLoS ONE, 2013
Recent studies have suggested that aberrant K-ras signaling is responsible for triggering immunological responses and inflammation-driven tumorigenesis.
Savvas Petanidis, Doxakis Anestakis, Maria Argyraki, Margarita Hadzopoulou-Cladaras, Athanasios Salifoglou   +4 more
doaj   +1 more source

Serum Cytokine Profile in Patients with Candidemia versus Bacteremia

Pathogens, 2021
Bloodstream Candida infections constitute a major threat for hospitalized patients in intensive care units and immunocompromised hosts. Certain serum cytokines play a decisive role in anti-microbial host defense.
Saad J. Taj-Aldeen, Fayaz Ahmad Mir, Siveen K. Sivaraman, Atqah AbdulWahab   +3 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

The relationship between past coronavirus infection and the content of serum interleukins in diseases of the nervous system

Acta Biomedica Scientifica
Background. The mediators of inflammation, which is the most important mechanism for the development of coronavirus infection, accompanied by various complications from the nervous system, both in the acute period of the disease and in the long term, are
P. E. Borodin
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The Relationship of Kidney Injury Molecule-1 and Interleukin-1 Beta with Hepatic and Renal Functions in Pregnant Women with Thyroid Disease

İstanbul Medical Journal, 2022
Introduction:Pregnancy is considered a low-grade inflammatory state presented with increased levels of pro-inflammatory markers. Despite the well-recognized association between inflammation and kidney injury, there is still a lack of available data ...
Emel Sağlam, Bennur Esen, Saadet Pilten, Vüsale Gözütok, Ahmet Engin Atay   +4 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Relationship between disorders of adipose tissue hormones and interleukins in patients with hypertension and comorbid pathology

Zaporožskij Medicinskij Žurnal, 2017
The purpose of research – was to improve the efficiency of diagnostics of arterial hypertension (AH) with comorbid disorders (diabetes mellitus (DM) and obesity) by studying hormones of adipose tissue (leptin and adiponectin) and the inflammatory markers
B. O. Shelest
doaj   +1 more source

PANCREATIC INVOLVEMENT IN LEPTOSPIROSIS [PDF]

Journal of IMAB, 2005
The research includes 84 patients with leptospirosis treated in Clinic at Infectious Diseases – Pleven. Mild course in 52,38%, moderate in 19,05%, and severe in 28,57% are established. Serum amylase level has been investigated in 37 cases.
Maria Atanasova, Galya I. Gancheva
doaj   +1 more source