Results 261 to 270 of about 105,051 (306)

Intermediate Filament Protein Inclusions

2004
Publisher Summary This chapter provides an overview of the intermediate filaments (IF) and mallory body (MB) as a prototype of intermediate filament and discusses related inclusions such as neurofibrillary tangles (NFTs), Lewy bodies, Lewy body-like or skeinlike inclusions, Rosenthal fibers, inclusions in skeletal muscle fibers, and mallory bodies ...
Kurt, Zatloukal, Conny, Stumptner, Andrea, Fuchsbichler, Elke, Janig, Helmut, Denk   +4 more
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Cytoskeleton | Intermediate Filament Linker Proteins: Plectin and BPAG1

2021
Owing to their structural diversity, functional versatility, and broad interaction profiles, intermediate filament linker proteins play a key role in the organization and dynamics of the cytoskeleton. As such they are involved in many fundamental cellular processes and play an important role in human diseases.
Wiche, Gerhard, Castanon, Maria J.
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Intermediate Filament Protein Structure Determination

2004
Publisher Summary X-ray crystallography is one of the few experimental methods that makes possible to study intermediate filament (IF) structure at atomic resolution; however, the prerequisite for a crystallographic analysis is the ability to produce macroscopic, well-ordered crystals.
Sergei V, Strelkov, Laurent, Kreplak, Harald, Herrmann, Ueli, Aebi   +3 more
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Evolutionary aspects in intermediate filament proteins

Current Opinion in Cell Biology, 2015
Intermediate filament (IF) proteins, together with tubulins and actins, constitute the majority of cytoskeletal proteins in metazoans. Proteins of the IF family fulfil increasingly diverse functions but share common structural features. Phylogenetic analysis within the metazoan lineage traces back their origin to a common lamin-like ancestor.
Annette, Peter, Reimer, Stick
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Implications of intermediate filament protein phosphorylation

Cancer and Metastasis Review, 1996
Intermediate filament (IF) proteins, a large family of tissue specific proteins, undergo several posttranslational modifications, with phosphorylation being the most studied modification. IF protein phosphorylation is highly dynamic and involves the head and/or tail domains of these proteins, which are the domains that impart most of the structural ...
N O, Ku, J, Liao, C F, Chou, M B, Omary
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Intermediate filament protein evolution and protists

Cytoskeleton, 2018
AbstractMetazoans evolved from a single protist lineage. While all eukaryotes share a conserved actin and tubulin‐based cytoskeleton, it is commonly perceived that intermediate filaments (IFs), including lamin, vimentin or keratin among many others, are restricted to metazoans. Actin and tubulin proteins are conserved enough to be detectable across all
Harald Preisner, Jörn Habicht, Sriram G. Garg, Sven B. Gould   +3 more
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Intermediate Filament-Associated Proteins

1990
Intermediate filaments (IF) comprise a set of ~ 10-nm-diameter cytoskeletal filaments that are distributed throughout the cytoplasm from the level of the nuclear surface to the region of the plasma membrane in most eukaryotic cells (Ishikawa et. al., 1968; Traub, 1985a; Wang et. al., 1985; Goldman et. al., 1986).
Hsi-Yuan Yang, Norman Lieska, Robert D. Goldman   +2 more
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Crystallographic Studies of Intermediate Filament Proteins

2017
Intermediate filaments (IFs), together with microtubules and actin microfilaments, are the three main cytoskeletal components in metazoan cells. IFs are formed by a distinct protein family, which is made up of 70 members in humans. Most IF proteins are tissue- or organelle-specific, which includes lamins, the IF proteins of the nucleus.
Dmytro, Guzenko, Anastasia A, Chernyatina, Sergei V, Strelkov   +2 more
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Myogenesis and the Intermediate Filament Protein, Nestin

Developmental Biology, 1994
We show that the intermediate filament protein nestin is expressed in myogenic cells and that multiple mechanisms regulate nestin expression at different stages of myogenesis. Cultured embryonic, fetal, and neonatal mouse limb myoblasts initially expressed nestin in the absence of the four muscle regulatory factors (MRFs) of the MyoD family, whereas ...
A M, Kachinsky, J A, Dominov, J B, Miller   +2 more
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Intermediate filament proteins in human sperm heads

Experimental Cell Research, 1986
Monoclonal antibodies made against human sperm cells have been characterized with regard to binding patterns and molecular coordinates of the recognized antigens. Antibodies T5 and T6 gave uniform binding to the acrosomal cap in an intact cell, and decreased to equatorial segment binding in an 'acrosome-reacted' cell.
D, Ochs, D P, Wolf, R L, Ochs
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