Results 241 to 250 of about 948,768 (269)

Prevalence of classical CD14++/CD16− but not of intermediate CD14++/CD16+ monocytes in hypoalphalipoproteinemia

International Journal of Cardiology, 2013
Giulia Chiesa, Angela Pirillo, Giuseppe Danilo Norata   +2 more
exaly   +4 more sources

Chronic Kidney Disease Is Characterized by Expansion of a Distinct Proinflammatory Intermediate Monocyte Subtype and by Increased Monocyte Adhesion to Endothelial Cells

Journal of the American Society of Nephrology, 2023
Significance Statement CKD is accompanied by abnormal inflammation, which contributes to progressive loss of functional renal tissue and accelerated cardiovascular disease. Although studies have documented that dysregulation of monocyte maturation and function is associated with CKD and its complications, it is not well ...
Sarah Cormican, Neema Negi, Serika D. Naicker, Md Nahidul Islam, Barbara Fazekas, Rachael Power, Tomás P. Griffin, M. Conall Dennedy, Briain MacNeill, Andrew F. Malone, Matthew D. Griffin   +10 more
openaire   +2 more sources

Total monocytes and intermediate and non-classical monocyte subpopulation are expanded in patients with systemic sclerosis

2019
Background: Many studies suggest that circulating monocytes are actively involved in the autoimmune disease systemic sclerosis (SSc). Circulating CD14+ monocytes form a heterogeneous population and can be differentiated into classical, intermediate and non-classical monocytes, and in addition, [for full text, please go to the a.m. URL]
Friedrich, K, Wagner, U, Baerwald, CGO, Pierer, M, Rossol, M   +4 more
openaire   +2 more sources

Circulating intermediate monocytes increase after elective percutaneous coronary intervention

European Heart Journal, 2023
Abstract Introduction Inflammation plays a central role in the pathogenesis of atherosclerosis and in the sequelae of percutaneous coronary intervention (PCI). Previous work demonstrated that intermediate monocytes (CD14++CD16+) are associated with adverse cardiovascular events, yet monocyte subset ...
I Merinopoulos, U Bhalraam, T Holmes, V Tsampasian, N Corballis, T Gunawardena, C Sawh, C Maart, T Wistow, A Ryding, S Eccleshall, J Smith, V Vassiliou   +12 more
openaire   +1 more source

Complement-mediated binding of monocytes to intermediate filaments in vitro.

The American journal of pathology, 1983
An in vitro model for complement (C)-mediated monocyte binding to injured cells is described. This model is based on the property of cytoskeletal intermediate filaments (IMF) to directly and independently activate serum C via the classic pathway. Fixed monolayers of cultured fibroblasts, endothelial cells, and L 132 epithelial cells were each used as ...
E, Linder, H, Helin, C M, Chang, T S, Edgington   +3 more
openaire   +1 more source

RelB regulates human dendritic cell subset development by promoting monocyte intermediates

Blood, 2004
In humans, epithelial Langerhans cells (LCs) and monocyte-derived/interstitial dendritic cells (DCs) constitute 2 myeloid DC sublineages. Molecular mechanisms involved in their development from common myeloid progenitors remain poorly defined. Here we demonstrate that the nuclear factor-κB (NF-κB) transcription factor RelB regulates the generation of ...
Barbara, Platzer, Almut, Jörgl, Sabine, Taschner, Bernhard, Höcher, Herbert, Strobl   +4 more
openaire   +2 more sources

Release of reactive oxygen and nitrogen intermediates from monocytes of patients with pulmonary tuberculosis

Scandinavian Journal of Clinical and Laboratory Investigation, 1995
M. tuberculosis, the aetiological agent of tuberculosis readily infects and multiplies within the macrophages of the host. Macrophage activation is known to occur through a series of stages, which results in the production of biologically active molecules such as the reactive oxygen and nitrogen intermediates.
V, Kumar, S K, Jindal, N K, Ganguly
openaire   +2 more sources

Fas mediates apoptosis in human monocytes by a reactive oxygen intermediate dependent pathway

The Journal of Immunology, 1996
Abstract Monocyte apoptosis has emerged as a central regulatory event in hemopoiesis and inflammation. Inflammatory cytokines can either promote or prevent monocyte apoptosis. To study the possible role of Fas Ag, a member of the TNF/nerve growth factor receptor family, in monocyte apoptosis, human peripheral blood monocytes activated
H D, Um, J M, Orenstein, S M, Wahl
openaire   +2 more sources

High Expression of Mincle in Intermediate Monocytes of Patients with Autoimmune Diseases

Journal of the American Society of Nephrology, 2021
Shuping Li, Lokyu Cheng, Tianjiao Cui, Lanyue Zhang, Xiuxun Tian, Zhizhuang J. Zhao, Yun Chen, Zhihua Zheng   +7 more
openaire   +1 more source

Intermediate monocytes are associated with moderate–high risk coronary artery calcium scoring

Journal of Investigative Medicine
Coronary artery calcium scoring (CCS) is a valuable non-invasive method for assessing atherosclerosis and performing risk stratification in patients with suspected coronary artery disease (CAD). Monocyte subsets play distinct roles in chronic inflammation and cardiovascular disease, potentially serving as biomarkers for CCS risk assessment.
Guihua Li, Lirui Yang, Tingting Feng, Tao Zhang, Lihui Zhou, Lu Wang, Lin Zhao   +6 more
openaire   +2 more sources