Results 111 to 120 of about 74,912 (281)

Non-limit state seismic earth pressure solution for finite soil mass considering intermediate principal stress

Shenzhen Daxue xuebao. Ligong ban
To investigate the distribution law of non-limit state seismic passive earth pressure in a finite soil mass under the translational (T-mode) pattern of a rigid retaining wall, and to overcome the limitations of existing seismic earth pressure models that
ZHOU Tong, DONG Yacheng, SHAN Yao, ZHAO Yu, XIAO Yi   +4 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Elastic–plastic criterion solution of deep roadway surrounding rock based on intermediate principal stress and Drucker–Prager criterion

Excavation‐induced rock failure and deformation near an underground opening boundary is closely associated with the intermediate principal stress, strain softening and rock mass dilation.
Fuxu Hao, Tian Jiang, Haofu Xu, Youyu Wei, Xinfeng Wang   +4 more
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Effects of Inherent Fabric Anisotropy and Intermediate Principal Stress on Constitutive Behavior of Uncemented and Cemented Sands

, 2016
Sand response changes with intensity of cementation bonds between sand grains, magnitude of intermediate principal stress and with fabric anisotropy. First a critical state bounding surface plasticity model is presented in this paper.
Mojtaba Rahimi, Rouzbeh Rasouli, Dave Chan, Alireza Nouri   +3 more
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Importance of the intermediate principal stress on failure and localization behavior in high porosity rocks

, 2014
The localization criterion developed by Rudnicki and Rice(1975), whereas intended for low porosity rocks has been found to be applicable to many other types of materials, including high porosity rocks such as sandstone.
Ingraham, Mathew
core  

Study on calculation of nonlimit passive earth pressure of unsaturated soil behind retaining wall

Scientific Reports
The accurate calculation of soil pressure behind retaining walls is essential for their design and construction. Currently, research on the non-limit soil pressure of unsaturated soil behind retaining walls is limited.
Yaxin Zhang, Wenchao Gu, Qiliang Xu, Shuai Zhang, Jie Huang, Shiyuan Huang   +5 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source