Results 41 to 50 of about 74,912 (281)
, 2022 The analytic solution for surrounding rock of roadway is of significance for stability analysis and roadway support. However, analytical solution for surrounding rock of roadway which took influences of water seepage, strain softening, dilatancy and ...
Fei Huang +4 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Failure in Confined Brazilian Tests on Sandstone
Applied Sciences, 2021 Strength of rocks in the confined tension region, where the minimum principal stress is tensile, has only infrequently been measured and is not well understood. Quasi-static confined Brazilian tests under a range of confining stresses (2.76 to 27.58 MPa)
Tyler Hagengruber +4 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Mechanical characteristics of plane strain unloading conditions with different initial states
Yantu gongcheng xuebaoFor the plane strain unloading issues in loess engineering, the lateral unloading plain strain tests on the loess with various initial states (intact, remolded and saturated) under different confining pressures and water contents are carried out by using
ZHANG Yu 1, 2, ZHAO Yang 1, LIU Keji 1, YE Sheng 1, LIU Jin 1, 2, DING Xiao 1, ZHANG Meng 1, QU Yonglong 1
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
, 2020 The reasonable determination of ultimate bearing capacity is crucial to an optimal design of shallow foundations. Soils surrounding shallow foundations are commonly located above the water table and are thus in an unsaturated state.
Changguang Zhang +3 more
core +1 more source
Energy Exploration & Exploitation, 2021 During horizontal well staged fracturing, there is stress interference between multiple transverse fractures in the same perforation cluster. Theoretical analysis and numerical calculation methods are applied in this study.
Weiyong Lu, Changchun He
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source