Results 41 to 50 of about 5,866,044 (229)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Advances in Civil Engineering, 2023 Tunnel opening or excavation in the strain-softening rock masses primarily leads to initial stress release and rock deformation. The increasing plastic shear strain induces a nonlinear variation of dilatancy in rock masses. Therefore, tunnel stability is
Xiuling Wang
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Seepage Flow Properties of a Columnar Jointed Rock Mass in a True Triaxial Experiment
Geofluids, 2021 A columnar jointed rock mass is a type of rock mass with strong geometric anisotropy and high interface permeability. Its seepage characteristics pose new challenges to the construction and maintenance of the Baihetan Hydropower Station on the Jinsha ...
Yanxin He +5 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
, 2020 The reasonable determination of ultimate bearing capacity is crucial to an optimal design of shallow foundations. Soils surrounding shallow foundations are commonly located above the water table and are thus in an unsaturated state.
Changguang Zhang +3 more
core +1 more source
Do principal surfaces of stress and strain always exist?
, 1997 Variations of stress and strain are commonly expressed by patterns of stress or strain trajectories: three mutually orthogonal families of continuous lines, parallel to maximum, intermediate and minimum stress or strain axes.
Lisle, Richard J., Treagus, Susan H.
core +7 more sources
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Failure in Confined Brazilian Tests on Sandstone
Applied Sciences, 2021 Strength of rocks in the confined tension region, where the minimum principal stress is tensile, has only infrequently been measured and is not well understood. Quasi-static confined Brazilian tests under a range of confining stresses (2.76 to 27.58 MPa)
Tyler Hagengruber +4 more
doaj +1 more source