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Abstract 19253: Chronic Hypobaric Hypoxia and Chronic Intermittent Hypobaric Hypoxia in Rats Leads to a Mismatch in the ADMA-NO Pathway

Circulation, 2013
Introduction: Chronic Hypoxia (CH) as well as chronic intermittent hypoxia (CIH) are associated with pathophysiological conditions like acute/chronic mountain sickness and pulmonary hypertension. In the manifestation of these diseases the endothelium and the L-arginine/NO pathway plays a crucial role.
Nicole Lueneburg   +5 more
openaire   +1 more source

Improvement of myocardial perfusion in coronary patients after intermittent hypobaric hypoxia

Journal of Nuclear Cardiology, 2006
Persons living at high altitude (exposed to hypoxia) have a greater number of coronary and peripheral branches in the heart than persons living at sea level. In this study we investigated the effect of intermittent hypobaric hypoxia on myocardial perfusion in patients with coronary heart disease.We studied 6 male patients (aged>or=53 years) with severe
Maria, del Pilar Valle   +10 more
openaire   +2 more sources

Erythropoietin acute reaction and haematological adaptations to short, intermittent hypobaric hypoxia

European Journal of Applied Physiology, 2000
This study aimed to determine whether brief hypoxic stimuli in a hypobaric chamber are able to elicit erythropoietin (EPO) secretion, and to effectively stimulate erythropoiesis in the short term. In two different experiments, a set of haematological, biochemical, haemorheological, aerobic performance, and medical tests were performed in two groups of ...
F A, Rodríguez   +8 more
openaire   +2 more sources

Involvement of Autonomic Nervous System in Antiarrhythmic Effect of Intermittent Hypobaric Hypoxia

Bulletin of Experimental Biology and Medicine, 2017
We studied the involvement of the autonomic nervous system in the antiarrhythmic effect of intermittent hypobaric hypoxia modeled by daily placing the rats into an altitude chamber at 405 mm Hg (5000 m above sea level). The antiarrhythmic effect of hypoxia was observed on the model of acute coronary occlusion/reperfusion in vivo, but not during ...
N V, Naryzhnaya   +3 more
openaire   +2 more sources

The effects of NO on the urea cycle pathway in short-term intermittent hypobaric hypoxia in rats

Respiratory Physiology & Neurobiology, 2021
Short-term hypoxic states can influence the health and life activities of lowlanders who travel shortly to high altitudes, in transitory situations, such as surgical ischemia-reperfusion (to one or several organs), and in some sporting activities, such as parachuting and extreme skiing, mountain rescue teams, regular commercial flight crews, in which ...
Hayarpi, Javrushyan   +2 more
openaire   +2 more sources

Chronic Intermittent Hypobaric Hypoxia Reduces Hypothalamic N-Methyl-d-Aspartate Receptor Activity and Sympathetic Outflow in Spontaneously Hypertensive Rats

High Altitude Medicine & Biology
Guo, Xinqi, Hongyu Ma, Ziye Cui, Qiyue Zhao, Ying Zhang, Lu Jia, Liping Zhang, Hui Guo, Xiangjian Zhang, Yi Zhang, Yue Guan, and Huijie Ma. Chronic intermittent hypobaric hypoxia reduces hypothalamic N-Methyl-d-Aspartate Receptor activity and sympathetic
Xinqi Guo   +11 more
semanticscholar   +1 more source

Chronic intermittent hypobaric hypoxia ameliorates iron metabolism disorder through ferritinophagy in collagen-induced arthritis mice.

Journal of Trace Elements in Medicine and Biology
AIM Rheumatoid arthritis (RA) is a chronic inflammatory disease that is often complicated by anemia of chronic disease (ACD). Studies have shown that the development of ACD is closely related to iron metabolism disorder.
Xuerui Fu   +10 more
semanticscholar   +1 more source

Comparison of the effects of chronic intermittent hypobaric hypoxia and continuous hypobaric hypoxia on hemodynamics in rats.

Sheng li xue bao : [Acta physiologica Sinica], 2015
The aim of this study is to investigate the effects of chronic intermittent hypobaric hypoxia (IHH) and chronic continuous hypobaric hypoxia (CHH) on hemodynamics under basic normoxia and acute hypoxia conditions and to find the difference of two types of chronic hypoxia.
Fang, Yuan   +7 more
openaire   +1 more source

[Effects of chronic intermittent hypobaric hypoxia on immune function in rat].

Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2013
To elucidate the effect of CIHH on cellular immunity and humoral immunity in rat by using flow cytometry method, immunohistochemistry method and electron microscopy techniques.Forty-eight male adult Sprague-Dawley rats were randomly divided into 4 groups: control(CON) group, 14 days CIHH (CIHH14) group, 28 days CIHH (CIHH28) group, 42 days CIHH (CIHH42)
Min, Shi   +7 more
openaire   +2 more sources

[Beneficial effects of intermittent hypobaric hypoxia on the body].

Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2015
Myocardial ischemia and reperfusion (I/R) is a common problem in clinic and there is no satisfactory method for prevention or treatment of I/R injury so far. Chronic intermittent hypobaric hypoxia (CIHH), similar to the concept of ischemia preconditioning (IPC)or altitude hypoxia adaptation (AHA), has been recognized to confer a protective effect on ...
Yi, Zhang, Zhao-Nian, Zhou
openaire   +1 more source

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