Results 51 to 60 of about 235,829 (264)

Risk and return in international corporate bond markets [PDF]

open access: yesJournal of International Financial Markets, Institutions and Money, 2019
Abstract Corporate bond returns in major developed economies increase with lower ratings and higher residual maturity. The performance of various factor models featuring corporate, sovereign and equity markets as factors suggests that the corporate bond factor plays a dominant role in explaining the variation of corporate bond returns.
Bekaert, Geert, De Santis, Roberto A.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

ANALISIS PENGARUH FAKTOR INTERNAL EMITEN TERHADAP BAGI HASIL INVESTOR PADA OBLIGASI SYARIAH MUDHARABAH DI INDONESIA

open access: yesJurnal Ekonomi Akuntansi dan Manajemen, 2015
This study aims to analyze the influence of internal factors of emitens that affect the investors profit-sharing to the mudharabah islamic bond in Indonesia.
Sri Rahayu, Isti Fadah, Novi Puspitasari
doaj  

Bonding Performance of Lithium Disilicate Veneers to Bioactive and Conventional Resin Cores using three types of luting agent: an in vitro study

open access: yesAl-Rafidain Dental Journal
Aims: The present study aimed to evaluate the shear bond strength (SBS) and internal adaptation of lithium disilicate veneers bonded to bioactive and conventional composite cores using various luting agents and bonding approaches. Materials and Methods:
Marwa J. Muhammad   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Multiple finances, margins of foreign direct investment and aggregate industry productivity [PDF]

open access: yesFinancial Theory and Practice, 2012
Based on a heterogeneous firm set-up, we model firms’ access to the internal capital market, bank finance as well as bond finance and investigate how firms’ adjustment among multiple sources of finance affects their performance in foreign direct ...
Jiarui Zhang, Lei Hou
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Optimization of Wood-Plastic Composites by Response Surface Method

open access: yesBioResources
To improve the material properties of wood-plastic composite, poplar fiber and polyethylene powder were used as the main components, a hot-press experiment was conducted using response surface methodology, and the relationship between processing ...
Feng Ji
doaj   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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