Results 71 to 80 of about 235,829 (264)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Investigation on the bond-slip behavior of recycled aggregate concrete-filled steel tube with studs.

PLoS ONE
This study investigates the influence of built-in studs on the bond behavior in recycled aggregate concrete-filled steel tube (RACFST) composite structures through push-out experiments.
Gehao Cai, Bing Sun, Sheng Zeng, Peng Yang, Jie Zhang   +4 more
doaj   +1 more source

Fluctuating hydrogen-bond network of the Hv1 ion channel

Computational and Structural Biotechnology Journal
The human voltage-gated proton channel Hv1 has an intriguing architecture, as (i) its voltage-sensing unit contributes to the proton permeation pathway and (ii) the single channel proton flux is too large to be supplied solely by diffusion from the ...
Honey Jain, Michalis Lazaratos, Peter Pohl, Ana-Nicoleta Bondar   +3 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Evaluation of Mechanical and Physical Properties of Particleboards with the Core Layer Made from Willow (Salix viminalis)

BioResources, 2013
The objective of this study was to investigate some mechanical and physical properties of three-layer particleboards with the core layer made from various willow (Salix viminalis) and industrial pine wood particle mixtures.
Arnold Wilczyński, Leszek Danecki
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

MODELING AND SIMULATION OF SINGLE LOOP PLANETARY TRANSMISSION SYSTEM BASED ON BOND GRAPH THEORY

Jixie qiangdu, 2017
Based on bond graph theory,considering the time-varying meshing stiffness,damping and tooth surface friction force of internal and external gear,using LuGre friction model,the bond graph model of NGW type planetary gear was established. And then,the bond
ZHANG BaoFeng, CUI YaHui, ZHANG An, LIU Kai, GUO Kun   +4 more
doaj  

Study of the block/grout interface in concrete and clay block masonry structures

Revista IBRACON de Estruturas e Materiais
This work aims to study the behavior of the block/grout interface for concrete and clay block masonry. This was achieved by push-out and pull-out experimental tests including reinforcement bar in the latter one.
O. S. Izquierdo, M. R. S. Corrêa, I. I. Soto   +2 more
doaj   +1 more source

The effects of surface bond relaxation on electronic structure of Sb2Te3 nano-films by first-principles calculation

AIP Advances, 2014
The effects of vertical compressive stress on Sb2Te3 nano-films have been investigated by the first principles calculation, including stability, electronic structure, crystal structure, and bond order.
C. Li, Y. F. Zhao, C. X. Fu, B. Q. Chi, Y. Y. Gong, C. Q. Sun   +5 more
doaj   +1 more source