Results 41 to 50 of about 804,657 (343)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
National response to internal displacement [PDF]
Forced Migration Review, 1998 In many cases the international community acts to protect and assist the world's internally displaced people in absence of responsible and effective national action. This is, at least partly, because countries experiencing crises of internal displacement
Jennifer McLean
doaj
, 2010 We present an experimental study of a droplet interacting with an ultrasonic surface acoustic wave (SAW). Depending on the amplitude of the wave, the drop can either experience an internal flow with its contact-line pinned, or (at higher amplitude) move ...
Baudoin, M. +3 more
core +2 more sources
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Internal displacement in eastern Burma [PDF]
Forced Migration Review, 2007 The history of post-independent Burma is characterisedby numerous conflicts in this extraordinarily heterogeneous country. Since military rule began in 196 2 Burmahas witnessed gross human rights abuses andmassive displacement.
Heather Rae
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Internal displacement beyond 2018: the road ahead
Forced Migration Review, 2018 The statistics and the challenges around internal displacement are daunting. However, much has been learned since the Guiding Principles on Internal Displacement were launched in 1998.
Alexandra Bilak, Avigail Shai
doaj
, 2019 Bimetallic catalysts can undergo segregation or redistribution of the metals driven by oxidizing and reducing environments. Bragg coherent diffraction imaging (BCDI) was used to relate displacement fields to compositional distributions in crystalline Pt ...
Cha, Wonsuk +13 more
core +1 more source
Nonlinear evolution of the m=1 internal kink mode in the presence of magnetohydrodynamic turbulence [PDF]
, 2006 The nonlinear evolution of the m=1 internal kink mode is studied numerically in a setting where the tokamak core plasma is surrounded by a turbulent region with low magnetic shear.
Andreas Bierwage +4 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source