Results 41 to 50 of about 822,379 (296)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Fuel injection pump for internal combustion engines Patent [PDF]

open access: yes, 1970
Variable displacement fuel pump for internal combustion ...
Danskin, J. H.
core   +1 more source

Droplets displacement and oscillations induced by ultrasonic surface acoustic waves: a quantitative study

open access: yes, 2010
We present an experimental study of a droplet interacting with an ultrasonic surface acoustic wave (SAW). Depending on the amplitude of the wave, the drop can either experience an internal flow with its contact-line pinned, or (at higher amplitude) move ...
Baudoin, M.   +3 more
core   +3 more sources

Node-to-segment and node-to-surface interface finite elements for fracture mechanics [PDF]

open access: yes, 2016
The topologies of existing interface elements used to discretize cohesive cracks are such that they can be used to compute the relative displacements (displacement discontinuities) of two opposing segments (in 2D) or of two opposing facets (in 3D ...
Paggi, M., Wriggers, P.
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Internal displacement beyond 2018: the road ahead

open access: yesForced Migration Review, 2018
The statistics and the challenges around internal displacement are daunting. However, much has been learned since the Guiding Principles on Internal Displacement were launched in 1998.
Alexandra Bilak, Avigail Shai
doaj  

National response to internal displacement [PDF]

open access: yesForced Migration Review, 1998
In many cases the international community acts to protect and assist the world's internally displaced people in absence of responsible and effective national action. This is, at least partly, because countries experiencing crises of internal displacement
Jennifer McLean
doaj  

ADAM10 Localization in Temporomandibular Joint Disk with Internal Derangement: An Ex Vivo Immunohistochemical Study [PDF]

open access: yes, 2016
The purpose of this study was to determine the presence of ADAM10 in temporomandibular joint disk with internal derangement. Twenty-five paraffin blocks of displaced temporomandibular joint (TMJ) disk specimens from earlier investigations were retrieved ...
Almeida, Luis Eduardo   +7 more
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Internal displacement and peace mediation [PDF]

open access: yesForced Migration Review, 2009
The need to protect the rights of persons displaced by conflict and find durable solutions to their displacement is inextricably linked to achieving a viable, sustainable peace.
Andrew Solomon
doaj  

Home - About - Disclaimer - Privacy