Results 61 to 70 of about 14,169 (221)

Influence of sampling schedules on dosimetry in radioligand therapies

, 2022
For internal dosimetry in radioligand therapies following the Committee on Medical Internal Radiation Dose, the time-integrated activity coefficients (TIACs) are required.
Rinscheid, Andreas
core   +1 more source

Wavelength‐Dependent Photobiomodulation Regulates Macrophage Polarization via Mitochondrial Dynamics and Metabolic Reprogramming

Advanced Science, EarlyView.
Light wavelength encodes distinct macrophage fates through mitochondrial and metabolic remodeling. Red 625 nm irradiation induces glycolysis, mitochondrial fission, and M1 polarization, whereas near‐infrared 850 nm irradiation promotes fatty acid oxidation, mitochondrial fusion, and M2 polarization.
Qiusheng Shi, Hao Jia, Jianfei Dong, Linhao Li, Jingqi Cao, Xun Chen, Zhenzhen Jia, Jing Na, Zhijie Yang, Xinyuan Chen, Yubo Fan, Shuhua Yue, Lisha Zheng   +12 more
wiley   +1 more source

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

Evaluation of the applicability of the inductively coupled plasma mass spectrometry method for special individual dosimetry monitoring

Радиационная гигиена, 2023
In the condition of modern radiation hazardous production, higher levels of personnel internal exposure are mainly due to the intake of radionuclides in situations caused by faulty equipment or wrong actions of personnel which can or do result in the ...
V. R. Batalov, A. B. Sokolova, A. V. Efimov, A. B. Dzhunushaliev   +3 more
doaj   +1 more source

Uncertainty in estimated intake for routine lung monitoring of Pu/Am

Radiation Protection and Environment, 2023
In routine monitoring of radiation workers to detect internal contamination due to Pu/Am, it is assumed that intake has occurred at the midpoint of the monitoring interval.
Minal Y Nadar, Sushanta Halder, Lokpati Mishra, Deepak K Akar, Indrasen S Singh, Pramilla D Sawant   +5 more
doaj   +1 more source

Biodistribution and internal radiation dosimetry of a companion diagnostic radiopharmaceutical, [68Ga]PSMA-11, in subcutaneous prostate cancer xenograft model mice

Scientific Reports, 2021
[68Ga]PSMA-11 is a prostate-specific membrane antigen (PSMA)-targeting radiopharmaceutical for diagnostic PET imaging. Its application can be extended to targeted radionuclide therapy (TRT).
Su Bin Kim, In Ho Song, Yoo Sung Song, Byung Chul Lee, Arun Gupta, Jae Sung Lee, Hyun Soo Park, Sang Eun Kim   +7 more
doaj   +1 more source

Deep Learning-Based Delayed PET Image Synthesis from Corresponding Early Scanned PET for Dosimetry Uptake Estimation

Diagnostics, 2023
The acquisition of in vivo radiopharmaceutical distribution through imaging is time-consuming due to dosimetry, which requires the subject to be scanned at several time points post-injection.
Kangsan Kim, Byung Hyun Byun, Ilhan Lim, Sang Moo Lim, Sang-Keun Woo   +4 more
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Understanding Current Trends and Advances in Transarterial Radioembolization Dosimetry

Diagnostics
Transarterial radioembolization (TARE) is an established therapy for primary and secondary hepatic malignancies. Outcomes depend heavily on dosimetry, which has evolved from empirical and body-surface-area methods to partition and voxel-based approaches.
Shamar Young, Kiyon Naser-Tavakolian, Abin Sajan, Stephen Reis, Gregory Woodhead, Tyler Sandow, Juan Gimenez, Kirema Garcia-Reyes, Zachary Berman, Venkatesh P. Krishnasamy   +9 more
doaj   +1 more source