Results 51 to 60 of about 1,417,954 (305)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Blanking by means of the finite element method [PDF]

open access: yes, 1998
This paper summarizes the results of simulating the blanking process by means\ud of the Finite Element Method. Unlike most of the research in this eld, the focus is not on the blanking process itself but on the deformed shape of a product after blanking.
Bolt, P.J.   +5 more
core   +1 more source

Finite element analysis of composite cylinder with centre cutout under axial load and internal pressure [PDF]

open access: yes, 2013
Results from Finite Element (FE) study on the response of composite cylinder shells with cutouts and subjected to internal pressure and axial compression are presented. The objective of the study is to improving the buckling load by applying the internal
Baharudin, B. T. Hang Tuah   +3 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Finite deformations of an electroelastic circular cylindrical tube [PDF]

open access: yes, 2016
In this paper the theory of nonlinear electroelasticity is used to examine deformations of a pressurized thick-walled circular cylindrical tube of soft dielectric material with closed ends and compliant electrodes on its curved boundaries.
Melnikov, Andrey, Ogden, Ray W.
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Position-Specific Movement Characteristics and Heart Rate Profile of Hearing-Impaired Futsal Players: A Simulated Game Analysis

open access: yesInternational Journal of Disabilities Sports and Health Sciences
The aim of this study is to compare the movement characteristics and heart rate (HR) response of hearing-impaired futsal players based on their playing positions during a simulated game.
Yasin Arslan   +2 more
doaj   +1 more source

Variable length strut with longitudinal compliance and locking capability [PDF]

open access: yes, 1985
A variable length strut device is illustrated for connecting two associated structures which includes an outer load bearing shell, a drive assembly, a length varying compliance assembly positioned by drive assembly, and a strut rod locking assembly.
Belew, R. R.
core   +1 more source

Intrinsic mechanism of phase locking in two-dimensional Josephson junction networks in presence of an external magnetic field

open access: yes, 1996
We present numerical simulations of the dynamics of two-dimensional Josephson junction arrays to study the mechanism of mutual phase locking. We show that in the presence of an external magnetic field two mechanisms are playing a role in phase locking ...
Basler M.   +5 more
core   +1 more source

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