Results 41 to 50 of about 5,698,869 (326)

A road map for point-of-care ultrasound training in internal medicine residency

The Ultrasound Journal, 2019
BackgroundEver-expanding uses have been developed for ultrasound, including its focused use at the bedside, often referred to as point-of-care ultrasound (POCUS).
Charles M. LoPresti, Daniel J. Schnobrich, Renee K. Dversdal, F. Schembri   +3 more
semanticscholar   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

Clinical commissioning of an adaptive radiotherapy platform: Results and recommendations

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Online adaptive radiotherapy platforms present a unique challenge for commissioning as guidance is lacking and specialized adaptive equipment, such as deformable phantoms, are rare. We designed a novel adaptive commissioning process consisting of end‐to‐end tests using standard clinical resources.
Kelly Kisling, Timothy D. Keiper, Daniela Branco, Grace Gwe‐Ya Kim, Kevin L Moore, Xenia Ray   +5 more
wiley   +1 more source

Long Term Evaluation of Glycemic Control in Patients with Type 2 Diabetes Receiving Either Alogliptin and Lansoprazole or Alogliptin Mono-therapy for 3 Months Followed by Alogliptin Mono-therapy:A Retrospective Analysis [PDF]

, 2015
Aims:This study was the retrospective analysis of the previous study named as APPLE study( study of combination effect of AlogliPtin and lansoPrazoLE on glycemic control in patients with type 2 diabetes), in which the effect of the combination therapy of
Department Of Internal Medicine, Dokkyo Medical University Koshigaya Hospital, Department Of Internal Medicine, Dokkyo Medical University Koshigaya Hospital, Department Of Internal Medicine, Dokkyo Medical University Koshigaya Hospital, Department Of Internal Medicine, Dokkyo Medical University Koshigaya Hospital, Department Of Internal Medicine, Dokkyo Medical University Koshigaya Hospital, Department Of Internal Medicine, Dokkyo Medical University Koshigaya Hospital, Department Of Internal Medicine, Dokkyo Medical University Koshigaya Hospital, Kenji Hara, Kohzo Takebayashi, Mariko Suetsugu, Rika Naruse, Takafumi Tsuchiya, Tomoko Terasawa, Toshihiko Inukai   +13 more
core   +1 more source

Education Outcomes in a Duty‐Hour Flexibility Trial in Internal Medicine

New England Journal of Medicine, 2018
Background Concern persists that inflexible duty‐hour rules in medical residency programs may adversely affect the training of physicians. Methods We randomly assigned 63 internal medicine residency programs in the United States to be governed by ...
S. Desai, D. Asch, L. Bellini, K. Chaiyachati, Manqing Liu, A. Sternberg, J. Tonascia, Alyssa Yeager, Jeremy M. Asch, J. Katz, M. Basner, D. Bates, K. Bilimoria, D. Dinges, O. Even-Shoshan, David M. Shade, J. Silber, Dylan S. Small, K. Volpp, J. Shea   +19 more
semanticscholar   +1 more source

The apo LETM1 F‐EF‐hand adopts a closed conformation that underlies a multi‐modal sensory role in mitochondria

FEBS Letters, EarlyView.
We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin, Danielle M. Colussi, Peter B. Stathopulos   +2 more
wiley   +1 more source

Application value of contrast‐enhanced ultrasound in preoperative localization of microwave ablation for primary hyperparathyroidism

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Background Ultrasonography (US) and 99mTechnetium‐sestamibi scintigraphy (99mTc‐MIBI) are currently first‐line imaging modalities to localize parathyroid adenomas with sensitivities of 80% and 84%, respectively. Therefore, finding other modalities to further improve the diagnostic accuracy for preoperative localization is critically needed ...
Fangyi Liu, Li Zang, Yunlin Li, Zhiwei Guan, Yang Liu, Xiaoling Yu, Zhiyu Han, Ping Liang   +7 more
wiley   +1 more source

The Effect of Switching from Either Mitiglinide or Glimepiride to Repaglinide on Both Glycemic Control and Oxidative Stress in Patients with Type 2 Diabetes [PDF]

, 2016
Aims:The goal of this study was to investigate the effect of switching from either the low dose sulfonylurea glimepiride(1?mg once daily)or the glinide mitiglinide(10?mg three times daily)to repaglinide(0.5?mg three times daily)on both glycemic control ...
Department Of Internal Medicine, Dokkyo Medical University Koshigaya Hospital, Department Of Internal Medicine, Dokkyo Medical University Koshigaya Hospital, Department Of Internal Medicine, Dokkyo Medical University Koshigaya Hospital, Department Of Internal Medicine, Dokkyo Medical University Koshigaya Hospital, Department Of Internal Medicine, Dokkyo Medical University Koshigaya Hospital, Department Of Internal Medicine, Dokkyo Medical University Koshigaya Hospital, Department Of Internal Medicine, Dokkyo Medical University Koshigaya Hospital, Kenji Hara, Kohzo Takebayashi, Mariko Suetsugu, Rika Naruse, Takafumi Tuchiya, Tomoko Terasawa, Toshihiko Inukai   +13 more
core   +1 more source

Education Indicators for Internal Medicine Point-of-Care Ultrasound: a Consensus Report from the Canadian Internal Medicine Ultrasound (CIMUS) Group

Journal of general internal medicine, 2019
Curriculum development and implementation for internal medicine point-of-care ultrasound (IM POCUS) continues to be a challenge for many residency training programs.
Anshula Ambasta, Marko Balan, Michael Mayette, A. Goffi, Sharon Mulvagh, Brian M. Buchanan, S. Montague, Shannon Ruzycki, Irene W. Y. Ma, Anshula Marko Marcus Brian Sharon E. Barry Janeve Gabriel Ambasta Balan Blouw Buchanan Card Chan Desy Demchu, Anshula Ambasta, Marko Balan, M. Blouw, Brian M. Buchanan, S. Card, B. Chan, Janeve Desy, Gabriel Demchuk, C. Gebhardt, A. Goffi, Samantha Halman, Brendan Kerr, Irene W. Y. Ma, Leslie Martin, Michael Mayette, S. Montague, Sharon Mulvagh, J. Ringrose, Shannon Ruzycki, J. Schaefer, Jeffrey Yu   +30 more
semanticscholar   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source