Results 61 to 70 of about 12,247,654 (298)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Paraconsistent Quasi-Set Theory [PDF]
, 2012 Paraconsistent logics are logics that can be used to base inconsistent but non-trivial systems. In paraconsistent set theories, we can quan- tify over sets that in standard set theories (that are based on classical logic), if consistent, would lead to
Krause, Décio
core
Fuzzy Soft Sets and its Application to Decision Making: A Short Case Study Involving the Health Sector [PDF]
The health sector faces uncertainty and complex decision-making scenarios, making traditional analytical tools insufficient. The fuzzy soft set theory has emerged as a powerful framework for modeling and reasoning with uncertain information, with ...
Adebisi, Sunday Adesina +1 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
On the averaging method for differential equations with delay
Electronic Journal of Differential Equations, 2002 In this paper, we present averaging results for delay differential equations under weak conditions. The main result is formulated in both classical mathematics and nonstandard analysis.
Mustapha Lakrib
doaj
Limiting amplitudes of fully nonlinear interfacial tides and solitons [PDF]
Nonlinear Processes in Geophysics, 2016 A new two-fluid layer model consisting of forced rotation-modified Boussinesq equations is derived for studying tidally generated fully nonlinear, weakly nonhydrostatic dispersive interfacial waves.
B. Aguiar-González, T. Gerkema
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Logical and Philosophical Remarks on Quasi-Set Theory [PDF]
, 2007 Quasi-set theory is a theory for dealing with collections of indistinguishable objects. In this paper we discuss some logical and philosophical questions involved with such a theory.
Krause, Décio, da Costa, Newton C. A.
core
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source