Results 71 to 80 of about 12,247,654 (298)
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Topological set theories and hyperuniverses [PDF]
, 2012 We give a new set theoretic system of axioms motivated by a topological intuition: The set of subsets of any set is a topology on that set. On the one hand, this system is a common weakening of Zermelo-Fraenkel set theory ZF, the positive set theory GPK ...
Fackler, Andreas
core +1 more source
The Set-Point Theory of Well-Being Needs Replacing: On the Brink of a Scientific Revolution? [PDF]
Set-point theory has dominated the field of subjective well-being (SWB). It has served as a classic Kuhn research paradigm, being extended and refined for thirty years totake in new results. The central plank of the theory is that adult set-points do not
Bruce Headey
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Finnish Journal of eHealth and eWelfare, 2015 Purpose Health care organizations are lacking a clear decision-making framework in IT investment decisions. This study aims at finding a practical tool able to take the different financial and non-financial factors into account.
Johanna Lamminen +3 more
doaj
Internal set theory approach to nonstandard analysis
, 2016 Although epsilon-delta analysis has enjoyed great success in giving rigor to modern mathematics, nonstandard analysis can be used to rigorously reformulate modern arguments with infinite and infinitesimal arguments.
Beauregard, Gregory
core
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Forcing in the alternative set theory. II [PDF]
, 1991 summary:By the technique of forcing, some new independence results are proved for the alternative set theory (AST) and similar weak theories: The scheme of choice is independent both of AST and of second order arithmetic, axiom of constructibility is ...
Sochor, Antonín, Sgall, Jiří
core +1 more source
SOFT UNION-THETA PRODUCT OF GROUPS [PDF]
Matrix Science MathematicSoft set theory provides a mathematically robust and algebraically versatile framework for modeling systems characterized by epistemic indeterminacy, vagueness, and parameter-dependent variability—features that pervade foundational inquiries in decision ...
Zeynep Ay, Aslıhan Sezgin
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source