Results 61 to 70 of about 87,380 (302)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Multiple ITS Copies Reveal Extensive Hybridization within Rheum (Polygonaceae), a Genus That Has Undergone Rapid Radiation [PDF]

, 2014
During adaptive radiation events, characters can arise multiple times due to parallel evolution, but transfer of traits through hybridization provides an alternative explanation for the same character appearing in apparently non-sister lineages.
A Gelman, A Keller, A Kovarik, A Kovarik, Ailan Wang, AL Wang, AR Griffin, AS Losina-Losinskaya, BB Liu, BG Baldwin, BG Baldwin, C Hughes, C Kiefer, C Koetschan, C Lexer, CL Schoch, D Harpke, D Harpke, D Harpke, D Schluter, DN Young, Dongshi Wan, DS Wan, DV Jobes, DY Zhang, DZ Li, ER Glor, ES Buckler, ES Buckler, F Herder, F Ma, F Ronquist, G Benson, G Besnard, G Bänfer, G Muir, G Sergey, GE McKinnon, GL Stebbins, GP Robideau, GW Grimm, I Alvarez, J Lihova, J Schultz, J Song, JD Thompson, JE Richardson, JF Manen, JJ Doyle, JQ Liu, JQ Liu, JQ Liu, Jun Wang, JW Ochieng, K Mao, K Tamura, KC Rowe, KJ Parsons, LH Rieseberg, LQ Xiao, LY Wang, M Arakaki, M Mayol, M Ryberg, M Wolf, MA Buchheim, MA Koch, MH Yang, NH Barton, O Seehausen, P Poczai, PR Grant, R Jaretzky, R Matyasek, RC Albertson, RH Nilsson, RI Milne, Richard Milne, RR Liu, RW Masueli, S Chen, S Dumolin-Lape'gue, S Gavrilets, S Guindon, S Hartmann, S Joly, S Shaw, Shilin Chen, T Denk, T Sang, TA Hall, TC Chin, TC Kao, TJ Givnish, TM Hardig, TM Porter, TT Xu, UK Schliewen, Xiaotao Bai, Xu Zhang, XY Zheng, Y Kita, YJ Wang, Yongshuai Sun, YP Hu, YS Sun   +105 more
core   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

New Genotypes of Enterocytozoon bieneusi Isolated from Sika Deer and Red Deer in China

Frontiers in Microbiology, 2017
To examine the occurrence and genotype distribution of Enterocytozoon bieneusi in cervids, 615 fecal samples were collected from red deer (Cervus elaphus) and sika deer (Cervus nippon) on 10 different farms in Henan and Jilin Province.
Jianying Huang, Zhenjie Zhang, Yong Yang, Yong Yang, Rongjun Wang, Jinfeng Zhao, Fuchun Jian, Changshen Ning, Longxian Zhang   +8 more
doaj   +1 more source

Alternaria leaf spot of broccoli caused by Alternaria alternata in Bangladesh

Plant Protection Science, 2022
This study aimed to isolate and characterise the pathogen associated with Alternaria leaf spot on broccoli and to evaluate the inhibitory effects of fungicides against it. We isolated and identified the fungal pathogen as Alternaria sp.
Sayma Tahsin Nira, Mohammad Farhad Hossain, Nur Uddin Mahmud, Oliul Hassan, Tofazzal Islam, Abdul Mannan Akanda   +5 more
doaj   +1 more source

Fungicide Resistance Genetics of Apple Scab fungus Venturia inaequalis [PDF]

, 2015
Apple scab, caused by the ascomycete fungus Venturia inaequalis, is considered the most devastating disease on domestic apple crops. Apples are the most important cultivated crop in temperate regions and the United States produced about 4.6 million tons ...
Reddel, Alexis LT
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

The Problem of Mixing up of Leishmania Isolates in the Laboratory: Suggestion of ITS1 Gene Sequencing for Verification of Species [PDF]

Iranian Journal of Parasitology, 2011
Background: Leishmaniasis is endemic in Iran. Different species of Leishmania (L.) parasites are causative agents of this disease. Correct identification of Leishmania species is important for clinical studies, prevention, and control of the diseases ...
H Mahmoudzadeh-Niknam, F Abrishami, M Doroudian, M Moradi, MH Alimohammadian, P Parvizi, GhR Hatam, M Mohebali, V Khalaj   +8 more
doaj   +1 more source

Molecular identification of Ixodid ticks of mithun from Nagaland

Indian Journal of Animal Sciences, 2016
An animal health check-up and treatment camp during the year 2015 for the free ranging mithun (Bos frontalis) organized at Khonoma and Jotsoma villages of Kohima district, Nagaland showed Ixodid tick infestation on these animals, with the ticks attached
J KCHAMUAH, S LAMA, P R DUTTA, O K RAINA, M H KHAN   +4 more
doaj   +1 more source

The systematic position of Gradsteinia andicola Ochyra (Donrichardsiaceae, Bryopsida) : evidence from nrDNA internal transcribed spacer sequences [PDF]

, 2000
Nuclear ribosomal DNA internal transcribed spacer (ITS) 1/2 sequences of the Colombian endemic Gradsteinia andicola were determined and compared with those of 16 other species of the Hypnales (Amblystegiaceae, Brachytheciaceae, Hypnaceae ...
Frahm, Jan-Peter, Stech, Michael
core