Results 61 to 70 of about 89,798 (345)
African Journal of Biotechnology, 2012 Molecular approaches are now being developed to provide a more rapid and objective identification compared to traditional phenotypic methods. Nuclear ribosomal DNA (nrDNA) targets, especially internal transcribed spacer 1 and 2 (ITS1 and ITS2), have been widely used for molecular identification of some plants and fungi.
Yan-Lin, S +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Fungicide Resistance Genetics of Apple Scab fungus Venturia inaequalis [PDF]
, 2015 Apple scab, caused by the ascomycete fungus Venturia inaequalis, is considered the most devastating disease on domestic apple crops. Apples are the most important cultivated crop in temperate regions and the United States produced about 4.6 million tons ...
Reddel, Alexis LT
core +1 more source
Cryptic transcripts from a ubiquitous plasmid origin of replication confound tests for cis-regulatory function. [PDF]
, 2012 A vast amount of research on the regulation of gene expression has relied on plasmid reporter assays. In this study, we show that plasmids widely used for this purpose constitutively produce substantial amounts of RNA from a TATA-containing cryptic ...
Hiraoka, Kei +3 more
core +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Frontiers in Veterinary Science, 2020 Enterocytozoon bieneusi is the most frequently diagnosed microsporidian species in humans and occurs in a wide range of animals. This study was conducted in Central Ethiopia to determine the prevalence and genotypes of E.
Teklu Wegayehu +4 more
doaj +1 more source
Molecular phylogeny of Oncaeidae (Copepoda) using nuclear ribosomal internal transcribed spacer (ITS rDNA). [PDF]
PLoS ONE, 2017 Copepods belonging to the Oncaeidae family are commonly and abundantly found in marine zooplankton. In the Mediterranean Sea, forty-seven oncaeid species occur, of which eleven in the Gulf of Naples.
Iole Di Capua +5 more
doaj +1 more source
Alternaria leaf spot of broccoli caused by Alternaria alternata in Bangladesh
Plant Protection Science, 2022 This study aimed to isolate and characterise the pathogen associated with Alternaria leaf spot on broccoli and to evaluate the inhibitory effects of fungicides against it. We isolated and identified the fungal pathogen as Alternaria sp.
Sayma Tahsin Nira +5 more
doaj +1 more source
Pythium sterilum sp. nov. isolated from Poland, Spain and France: its morphology and molecular phylogenetic position [PDF]
, 2017 In a survey of Phytophthora species associated with forest decline in Spain, Poland and France, we found three Pythium isolates, which have been characterized with internal transcribed spacer rRNA gene sequences and with classical morphological ...
Belbahri, Lassaad +4 more
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source