Results 121 to 130 of about 8,919 (253)

Phenomenal Conservatism and the Internalist Intuition [PDF]

open access: yes, 2006
Externalist theories of justification create the possibility of cases in which everything appears to one relevantly similar with respect to two propositions, yet one proposition is justified while the other is not.
Huemer, Michael
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

GETTİER SONRASI EPİSTEMOLOJİDE DESCARTES ODAKLI BİLGİ TANIMI TARTIŞMALARI

open access: yesFelsefe Dünyası, 2014
E. Gettier’in “Is Justified True Belief Knowledge?”(GerekçelendirilmişDoğru İnanç Bilgi midir?) adlı küçük makalesi, felsefe tarihinin en etkili yazılarındanbirisi olmakla kalmayıp, aynı zamanda felsefenin özgün alanlarınınbaşında gelen epistemolojide de
Nebi Mehdiyev
doaj  

Justification and Rationality from the perspective of the Dual System Theory of Reasoning [PDF]

open access: yesIdeas y Valores, 2009
A common assumption in epistemology is that there is an important connection between the notions of justification and rationality. However, this connection is unclear since there is no consensus about what rationality is or what a “correct” notion of ...
Jonatan García-Campos
doaj  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Is Epistemology Autonomous? [PDF]

open access: yes, 2019
Greco, Daniel
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Externalism and knowledge: how to follow rules

open access: yesОмский научный вестник: Серия "Общество. История. Современность"
The aim of the paper is to show that Kripke-Wittgenstein’s rule-following paradox assumes the premise of epistemic internalism that inappropriately restricting the admissible answers about how agents can know the rules or meanings of linguistic ...
A. M. Kardash
doaj   +1 more source

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