Results 61 to 70 of about 8,905 (245)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Luka eksplanacyjna a pojęcia własności fenomenalnych stanowisko Josepha Levine’a ( Explanatory gap and the concept of phenomenal properties: Joseph Levine’s view) [PDF]
Analiza i Egzystencja, 2012 The explanatory gap problem arises in the context of the mind-body relation, and especially the phenomenal concepts-physical concepts relation. It is posed as a question about the method which is appropriate for the reduction of consciousness to physical
Adriana Schetz
doaj
Освітній дискурс, 2019 The article examines the dominant paradigm and current research state of the theoretical and practical dimension of cooperative behavior based on the notion of “collective intentionality” scrutinized within the framework of analytic social philosophy ...
Frol Revin
doaj +1 more source
Moral disengagement and the motivational gap in climate change [PDF]
, 2019 Although climate change jeopardizes the fundamental human rights of current as well as future people, current actions and ambitions to tackle it are inadequate.
Diependaele, Lisa +2 more
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A Better Disjunctivist Response to the 'New Evil Genius' Challenge [PDF]
, 2017 This paper aims for a more robust epistemological disjunctivism (ED) by offering on its behalf a new and better response to the ‘new evil genius’ problem. The first section articulates the ‘new evil genius challenge’ (NEG challenge) to ED, specifying its
Shaw, Kegan J.
core +1 more source
Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja +8 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
On the significance of L. Zagzebski’s results for solving the Gettier problem
Интеллект. Инновации. ИнвестицииThe article is devoted to the analysis of the authoritative research results of L. Zagzebski on the Gettier problem, which has not been solved for many years.
R. A. Yartsev
doaj +1 more source
Preservationism in the Epistemology of Memory [PDF]
, 2016 Preservationism states that memory preserves the justification of the beliefs it preserves. More precisely: if S formed a justified belief that p at t1 and retains in memory a belief that p until t2, then S's belief that p is prima facie justified via ...
Frise, Matthew
core +1 more source