Results 121 to 130 of about 621,017 (390)
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Preferencing, internalization and inventory position [PDF]
We present a model of market-making in which dealers differ by their current inventory positions and by their preferencing agreements. Under preferencing, dealers receive captive orders that they guarantee to execute at the best price.
Lescourret, Laurence +1 more
core +1 more source
Evidence for the participation of actin microfilaments and bristle coats in the internalization of gap junction membrane. [PDF]
, 1979 William J. Larsen +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
COMPANY EVALUATION USING THE DISCOUNTED NET CASH FLOW METHOD [PDF]
The tendency of passing from the internalization to the globalization of the economic life was an outstanding feature of the business background evolution on worldwide scale- during 20th century.
Dan Florentin Sichigea, Nicolae Sichigea
core
Characterization of Uptake and Internalization of Exosomes by Bladder Cancer Cells
BioMed Research International, 2014 Bladder tumors represent a special therapeutic challenge as they have a high recurrence rate requiring repeated interventions and may progress to invasive or metastatic disease.
Carrie A. Franzen +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
wiley +1 more source
International trade and internal organization [PDF]
Journal of Economic Behavior & Organization, 2000 Abstract Informal discussions on international trade attribute much importance to organizational differences. Nevertheless, economic theories of international trade have not been extended to incorporate this important element. This paper integrates theories of internal organization with a model of international trade by adding another dimension — how
openaire +2 more sources
PLASMA MEMBRANE AND INTERNALIZED IMMUNOGLOBULINS OF LYMPH NODE CELLS STUDIED WITH CONJUGATES OF ANTIBODY OR ITS FAB FRAGMENTS WITH HORSERADISH PEROXIDASE [PDF]
, 1974 Jean-Claude Antoine +4 more
openalex +1 more source
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source