Results 221 to 230 of about 621,017 (390)

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Case Report: A novel CXCR4 variant (p.S341Y) in a family with a pathogenic NFKB1 variant and variable clinical manifestations. [PDF]

Front Immunol
Yilmaz M, Zmajkovicova K, Miller RZ, Blair G, Ellison M, Ujhazi B, Lopez MC, Dasso JF, Bledsoe JR, Csomos K, Maierhofer B, Badarau A, Pereira JP, Kanarek H, Geier CB, Walter JE.   +15 more
europepmc   +1 more source

Temperature-dependent internalization of virus glycoproteins in cells infected with a mutant of Semliki Forest virus. [PDF]

, 1982
Pentti Ukkonen, Jaakko Saraste, Kai Korpela, Marja Pesonen, Leevi Kääriäinen   +4 more
openalex   +1 more source

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

FEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno, Aki Terasaki, Yuiko Imai, Yuri Kimura, Yuna Kojima, Misa Irie, Koya Odaira, Mina Noura, Shuichi Okamoto, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa   +12 more
wiley   +1 more source

AChR Autoantibody Pathogenic Properties Are Heterogeneously Distributed and Undergo Temporal Changes Among Patients With Myasthenia Gravis. [PDF]

Neurol Neuroimmunol Neuroinflamm
Khani-Habibabadi F, Roy B, Pham MC, Obaid AH, Filipek B, Nowak RJ, O'Connor KC.   +6 more
europepmc   +1 more source

Regulation of insulin receptor internalization in vascular endothelial cells by insulin and phorbol ester.

, 1987
HARUMI L. HACHIYA, Shin Takayama, Morris F. White, George L. King   +3 more
openalex   +1 more source

Osmotically induced microinjection of ricin bypasses a ricin internalization defect in a Chinese hamster ovary mutant cell line. [PDF]

, 1984
Pratiti Ghosh, Robert B. Wellner, Hao Wu
openalex   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

ICAM-1-mediated Src signaling pathway plays a pivotal role in encephalomyocarditis virus entry. [PDF]

J Virol
Lian R, Dou X, Wang N, Li S, Xie J, Li X, Yang Y, Wen Y, Li H, Feng R.   +9 more
europepmc   +1 more source

Rapid constitutive internalization and externalization of epidermal growth factor receptors in isolated rat hepatocytes. Monensin inhibits receptor externalization and reduces the capacity for continued endocytosis of epidermal growth factor.

, 1988
I P Gladhaug, Thoralf Christoffersen
openalex   +1 more source