Results 71 to 80 of about 9,501,817 (347)
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Response to the Repeal of China’s One-Child Policy: Part 1 – How Revolutionary? [PDF]
, 2015 Last week, it was announced that China’s one-child policy, first introduced in the late 1970s, was to be formally adjusted. In the first of a series of posts, academics from the Department of International Development examine the various reasons behind ...
International Development,
core
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Disrupting the Old Periphery: Alternative Media, Inequality and Counter-Mapping in Brazil
Westminster Papers in Communication and Culture, 2018 Media discourse on the periphery in Brazil has historically mirrored the country’s socioeconomic divides. The periphery used to be where precarious dwellings predominate: a way of ‘behaviour’ of the poor, their social class, or an aspect at one’s ...
Helton Levy
doaj +2 more sources
Introducing the MSc International Development & Humanitarian Emergencies – Stuart Gordon [PDF]
, 2015 Next in line of our new introductory videos is the MSc International Development and Humanitarian ...
International Development,
core
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
A Special Issue of World Development, 2014 [PDF]
, 2014 Decentralization and ...
International Development,
core
Molecular Oncology, EarlyView.Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef +10 more
wiley +1 more source
What are the ID staff reading in 2014? [PDF]
, 2014 What books are the International Development department staff looking forward to reading in ...
International Development,
core
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source