Results 11 to 20 of about 18,854,124 (268)

Simplified Method for International Normalized Ratio (INR) Derivation Based on the Prothrombin Time/INR Line: An International Study [PDF]

Clinical Chemistry, 2010
BACKGROUND The need to perform local International Sensitivity Index (ISI) calibrations and in particular the requirement for a manual method for prothrombin time (PT) determination, have proved to be obstacles to application of the WHO scheme for PT standardization.
Poller, Leon, Ibrahim, Saied; id_orcid 0000-0002-2657-8834, Keown, Michelle, Pattison, Albert, Jespersen, Jørgen   +4 more
openaire   +5 more sources

Variability in the results of inr (international normalized ratio): a comparison of six commercial thromboplastin brands

Semina: Ciências Biológicas e da Saúde, 2015
Introduction: The efficacy and safety in treatment with oral anticoagulants are dependent on the monitoring of the effect of anticoagulants by the prothrombin time (PT).
Fernanda Daniela Serralvo, Jacinta Ludovico Zamboti, José Wander Bregano   +2 more
doaj   +2 more sources

The introduction of the international normalized ratio as a breakthrough event in the history of thrombosis

Bleeding, Thrombosis and Vascular Biology
Very few among the youngest readers of this Journal would think about the introduction of the international normalized ratio (INR) as a breakthrough event in the history of thrombosis...
Armando Tripodi
doaj   +2 more sources

International normalized ratio self-testing and self-management: improving patient outcomes

Vascular Health and Risk Management, 2016
Matteo Pozzi,1 Julia Mitchell,2 Anna Maria Henaine,3 Najib Hanna,4 Ola Safi,4 Roland Henaine2 1Department of Adult Cardiac Surgery, “Louis Pradel” Cardiologic Hospital, Lyon, France; 2Department of Congenital Cardiac Surgery, “Louis ...
Pozzi M, Mitchell J, Henaine AM, Hanna N, Safi O, Henaine R   +5 more
doaj   +1 more source

Thrombolysis in stroke patients: Comparability of point-of-care versus central laboratory international normalized ratio. [PDF]

PLoS ONE, 2018
In acute stroke patients, thrombolysis is one gold standard therapy option within the first four hours after the ischemic event. A contraindication for thrombolysis is an International Normalized Ratio (INR) value >1.7.
Ramona C Dolscheid-Pommerich, Sarah Dolscheid, Lars Eichhorn, Birgit Stoffel-Wagner, Ingo Graeff   +4 more
doaj   +2 more sources

Direct oral anticoagulant: Review article

Journal of Family Medicine and Primary Care, 2022
Venous thromboembolism (VTE) and atrial fibrillation (AF) is a major burden on the health care system. The average occurrence of venous thromboembolism annually is around 108 per 100,000 person-year.
Abdulrahman Nasiri, Ahmed AlQahtani, Nora H Rayes, Rawan AlQahtani, Reem Alkharras, Hamad Alghethber   +5 more
doaj   +1 more source

Drug interactions between ALK inhibitors and warfarin with concurrent use of bucolome: a case report

Journal of Pharmaceutical Health Care and Sciences, 2023
Background Alectinib, crizotinib, and ceritinib, are anaplastic lymphoma kinase-tyrosine kinase inhibitors (ALK-TKIs) that exhibit high protein binding, and their metabolism is associated with the cytochrome P450 (CYP) isoenzymes 2C9 or 3A4.
Takashi Kato, Yusuke Kunimoto, Manabu Kitagawa, Yuichiro Asai, Tomoko Kimyo, Hiromasa Nakata, Mamoru Takahashi, Hirofumi Chiba, Hiroki Takahashi, Atsushi Miyamoto, Masahide Fukudo   +10 more
doaj   +1 more source

Correlation of prehospital point-of-care international normalized ratio to laboratory-based international normalized ratio in acute traumatic coagulopathy

, 2022
Acute traumatic coagulopathy (ATC) is associated with increased mortality and hospital transfusion requirements.1,2 Accurate prehospital identification of ATC may improve outcomes by expediting care.
Lachlan Parker, Emma Bosley, Stephen Rashford, Meister, Matthew, Rashford, Stephen, Matthew Meister, Glenn Ryan, Ryan, Glenn, Bodnar, Daniel, Lam, Alfred K, Parker, Lachlan, Daniel Bodnar, Martin Wullschleger, Wullschleger, Martin, Bosley, Emma, Alfred K. Lam   +15 more
core   +1 more source

Targeted decrease of portal hepatic pressure gradient improves ascites control after TIPS

Hepatology, EarlyView., 2022
The river diagram demonstrates that after transjugular intrahepatic portosystemic shunt insertion (TIPS) the majority of patients without ascites and 50% of the patients with ascites detectable at ultrasound, show the best response in the long term follow‐up.
Alexander Queck, Louise Schwierz, Wenyi Gu, Philip G. Ferstl, Christian Jansen, Frank E. Uschner, Michael Praktiknjo, Johannes Chang, Maximilian J. Brol, Filippo Schepis, Manuela Merli, Christian P. Strassburg, Jennifer Lehmann, Carsten Meyer, Jonel Trebicka   +14 more
wiley   +1 more source

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

Hepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole, Kristin Kaasen Jørgensen, Kristian Holm, Peder R. Braadland, Malin Holm Meyer‐Myklestad, Asle Wilhelm Medhus, Dag Henrik Reikvam, Alexandra Götz, Krzysztof Grzyb, Kirsten Muri Boberg, Tom Hemming Karlsen, Martin Kummen, Johannes R. Hov   +12 more
wiley   +1 more source