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SummaryThe effects of argatroban, a direct thrombin inhibitor, on the International Normalized Ratio (INR), activated partial thromboplastin time (aPTT) and functional factor X during warfarin co-administration were established to provide means to interpret INRs during argatroban/warfarin co-therapy. Twenty-four subjects receiving warfarin (7.5 mg, day
D K Jorkasky
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The International Normalized Ratio (INR): a review for orthopaedic nurses
Journal of Orthopaedic Nursing, 2001Abstract Patients undergoing anticoagulant therapy are not uncommon on orthopaedic wards. It is, therefore, important for orthopaedic nurses to have a sound understanding of the International Normalized Ratio (INR) in their professional practice. The authors provide background to the use of INR in contrast to prothrombin time (PT), describe how the ...
James A. Rankin, Karen L. Then
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Dietary Vitamin K Variability Affects International Normalized Ratio (INR) Coagulation Indices
International Journal for Vitamin and Nutrition Research, 2006Background: Changes in daily vitamin K intake may contribute to marked variations in the International Normalized Ratio (INR) coagulation index in patients receiving oral warfarin anticoagulant therapy, with potentially serious adverse outcomes. Thus, patients receiving warfarin therapy are routinely counseled regarding this drug-nutrient interaction ...
Johanna T. Dwyer +2 more
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Standardization of Prothrombin Time/International Normalized Ratio (PT/INR) [PDF]
The prothrombin time (PT) represents the most commonly used coagulation test in clinical laboratories. The PT is mathematically converted to the international normalized ratio (INR) for use in monitoring anticoagulant therapy with vitamin K antagonists ...
Mehran Bahraini, Akbar Dorgalaleh
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Background: The original WHO procedure for prothrombin time (PT) standardization has been almost entirely abandoned because of the universal use of PT coagulometers.
J Jespersen, S Ibrahim, L Poller
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Clinical Chemistry and Laboratory Medicine, 2017
Una Ørvim Sølvik, Anne Stavelin
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Una Ørvim Sølvik, Anne Stavelin
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ObjectivesTo investigate association between quality of life (QoL) and International Normalized Ratio (INR) control, with the secondary aim of assessing QoL using generic and anticoagulation-specific, the Short Form Health Survey (SF-12) and the Duke ...
Syed Imran Ahmed, Syed Shahzad Hasan
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International Normalized Ratio (INR)
The Nurse Practitioner, 1995Oral anticoagulant therapy may be inappropriately managed and thus potentially place the warfarin-treated patient at an increased and unnecessary risk of bleeding or thromboembolic complications. This management issue is largely due to variations in measuring the pro-thrombin time.
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Clinical Toxicology, 2021
Previous literature suggests a laboratory interference of n-acetylcysteine (NAC) with prothrombin time (PT) and the international normalized ratio (INR). Early publications focused on this interaction in the setting of an acetaminophen overdose and evaluated the INR of patients receiving intravenous NAC.
Faisal Syed Minhaj +5 more
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Previous literature suggests a laboratory interference of n-acetylcysteine (NAC) with prothrombin time (PT) and the international normalized ratio (INR). Early publications focused on this interaction in the setting of an acetaminophen overdose and evaluated the INR of patients receiving intravenous NAC.
Faisal Syed Minhaj +5 more
openaire +2 more sources

