Results 71 to 80 of about 18,854,124 (268)
Should we Test the Prothrombin Time in Anticoagulated Epistaxis Patients?
Epistaxis is one of the most frequent emergencies in rhinology. Patients using anticoagulative medication are at increased risk for epistaxis. We evaluated the prothrombin time and the international normalized ratio (INR) in anticoagulated epistaxis ...
Michael B. Soyka M.D. +1 more
doaj +1 more source
Introduction: The aim of our study was to explore if there exists a circannual rhythm in INR as fluctuations in anti-coagulation can have serious consequences in patients with mechanical heart valve prosthesis.
Samir Alshnaikat +7 more
doaj +1 more source
Admission International Normalized Ratio and Acute Infarct Volume in Ischemic Stroke
Objective: The level of anticoagulation at the time of stroke onset may influence the size, composition, and dissolution rate of the occlusive clot. We explored the relation between admission international normalized ratio (INR) and acute infarct volume ...
Singhal, Aneesh B. +7 more
core +1 more source
Butyrate ameliorates acute‐on‐chronic liver failure by regulating macrophage polarization
Multi‐omics profiling identifies progressive microbiota‐metabolism‐immunity axis dysfunction in acute‐on‐chronic liver failure (ACLF), characterized by gut dysbiosis, reduced butyrate production, intestinal barrier disruption, microbial translocation, and pro‐inflammatory macrophage polarization, thereby exacerbating hepatic inflammation and fibrosis ...
Jing Xiao +10 more
wiley +1 more source
International Normalized Ratio (INR), which standardizes prothrombin time (PT) during oral anticoagulation, has been extended to standardize PT in liver diseases and is included in prognostic models such as the Model for End stage Liver Disease (MELD ...
Poupon, Raoul +4 more
core +1 more source
This study demonstrates that the model for end‐stage liver disease (MELD) score significantly underestimates 90‐day mortality in acute‐on‐chronic liver failure (ACLF) patients (AUC: 0.556) compared to non‐ACLF patients (area under the receiver operating characteristic curve [AUC]: 0.848).
Guanghou Chen +5 more
wiley +1 more source
Introduction: Oral anticoagulation with warfarin is indicated for patients with prosthetic heart valves. The effects of religious fasting during Ramadan month (in the Islamic calendar) on anticoagulation aren’t clear.
Muhammad O. Awiwi +5 more
doaj +1 more source
ABSTRACT Background/Purpose This study evaluated the association between institutional advanced hepatobiliary‐pancreatic (HBP) surgical volume and operative mortality for pancreaticoduodenectomy (PD) and advanced hepatectomy using data from the Japanese National Clinical Database.
Yoshitaro Shindo +11 more
wiley +1 more source
Using Labs Wisely: A collaboration between Choosing Wisely Canada and over 150 Canadian hospitals
Abstract Background Many in‐hospital laboratory tests are unnecessary. Unnecessary testing is associated with patient harm, fiscal inefficiency, and environmental waste. Objectives In 2021, Choosing Wisely Canada launched the Using Labs Wisely (ULW) hospital collaborative to (1) build national expertise on reducing unnecessary testing, (2) share ...
Thomas Bodley +8 more
wiley +1 more source
Understanding and interpreting composite outcomes in clinical research
Abstract Composite outcomes combine multiple endpoints into a single measure. They can capture overall treatment effects and increase statistical power, but have important interpretive challenges. Components of the outcome may vary in clinical importance, frequency, and treatment effect.
Mari Takashima +3 more
wiley +1 more source

