Results 81 to 90 of about 18,854,124 (268)

Nonsteroidal Anti-Inflammatory Drugs Decrease Coagulopathy Incidence in Severe Burn Patients

open access: yesEuropean Burn Journal
The study investigated the impact of nonsteroidal anti-inflammatory drugs (NSAIDs) on burn-induced coagulopathy in severely burned patients. Patients with a greater than 20% TBSA were identified in the TriNetX research network and categorized into ...
Lyndon Huang   +10 more
doaj   +1 more source

Portal vein peak systolic velocity is a useful noninvasive predictor of high‐risk varices in biliary atresia

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Portal vein (PV) flow velocity is considered an indicator of portal hypertension. However, few studies have evaluated the predictive performance of PV flow velocity for high‐risk varices (HRV) in children with biliary atresia (BA). In this study, we evaluated the predictive performance of PV peak systolic velocity (PSV) for HRV in ...
Tomoya Fukuoka   +8 more
wiley   +1 more source

Therapeutic plasma exchange in Amatoxin‐associated pediatric acute liver failure—Results from the Amanita‐PEX study

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Pediatric acute liver failure (PALF) is a rare but life‐threatening condition. Amanita poisoning can lead to PALF with rapid clinical deterioration. Therapeutic plasma exchange (TPE) has been proposed as a potential supportive intervention and is established in adult acute liver failure.
Klaus Stahl   +26 more
wiley   +1 more source

International Normalized Ratio (INR), coagulation factor activities and calibrated automated thrombin generation - influence of 24 h storage at ambient temperature

open access: yes, 2010
International Normalized Ratio (INR) measurements are used to monitor oral anticoagulation therapy with coumarins. Single coagulation factor activities and calibrated automated thrombin (CAT) generation are considered as more advanced methods for ...
Christensen, T D   +11 more
core   +1 more source

A preterm neonate with infantile liver failure syndrome 1 due to leucyl‐tRNA synthetase 1 gene (LARS1) mutations with a histopathologic phenotype of neonatal hemochromatosis

open access: yesJPGN Reports, EarlyView.
Abstract We report a case of a premature, growth‐restricted female infant with feeding intolerance and coagulopathy, treated initially for sepsis, who progressed to neonatal acute liver failure and end‐stage hepatic encephalopathy after a prolonged hospitalization with extensive diagnostic evaluation, and was found by autopsy to have histopathologic ...
Adrienne Bruder   +3 more
wiley   +1 more source

Biochemical testing and pathology reveal rare cause of pediatric acute liver failure: Hyperornithinemia‐hyperammonemia‐homocitrullinuria syndrome

open access: yesJPGN Reports, EarlyView.
Abstract Hyperornithinemia‐hyperammonemia‐homocitrullinuria (HHH) syndrome is a rare metabolic condition that can cause lethargy, ataxia, tachypnea, nausea, vomiting, seizures, coma, and acute liver failure. We present a 26‐month‐old female with acute liver failure who was diagnosed with HHH 1 week after admission. Histology revealed an acute hepatitic
Tierra L. Mosher   +6 more
wiley   +1 more source

Comparison of the INR Values Measured by CoaguChek XS Coagulometer and Conventional Laboratory Methods in Patients on VKA Therapy

open access: yes, 2017
Background: Warfarin, which is a widely used oral anticoagulant, has a narrow therapeutic window and requires regular international normalized ratio (INR) monitoring to maintain optimal anticoagulation.
ASTARCIOĞLU, MEHMET ALİ   +8 more
core   +1 more source

A hepatic enigma: Pediatric presentation of primary biliary cholangitis

open access: yesJPGN Reports, EarlyView.
Abstract Primary biliary cholangitis (PBC) is a chronic autoimmune condition characterized by destruction of intrahepatic bile ducts, leading to fibrosis and cirrhosis of the liver. It is an extremely rare pediatric disease with very few pediatric cases reported to date. Here, we report the case of a 14‐year‐old female who presented with elevated liver
Sindhura Kasturi   +3 more
wiley   +1 more source

Standardized Tool for Prophylaxis (SToP) of venous thromboembolism: An asynchronous curriculum to enhance venous thromboembolism prevention in pediatric inflammatory bowel disease

open access: yesJPGN Reports, EarlyView.
Abstract Objectives Compared to those without inflammatory bowel disease (IBD), pediatric patients with IBD are at three‐ to sevenfold increased risk for venous thromboembolism (VTE), a complication associated with substantial morbidity and mortality.
Hilary K. Michel   +4 more
wiley   +1 more source

Health risk assessment of heavy metal accumulation in fruits exposed to geothermal waters: a case study and global implications

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The present study investigated the potential health risks of heavy metals (HMs) in the fruits and leaves of mulberry and sour cherry trees exposed to water from Sivas geothermal basin (Turkey). RESULTS The target HMs were ranked according to their hazard index as: Cd < Pb < Zn < Cu < Ni < Mn < Cr. The total hazard index for mulberry
E Işıl Arslan Topal   +3 more
wiley   +1 more source

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