Results 161 to 170 of about 37,744 (224)

Add‐on treatment with vinpocetine reduces seizure frequency and improves comorbidities in patients with loss‐of‐function γ‐aminobutyric acid type A receptor variants

open access: yesEpilepsia, EarlyView.
Abstract Objective The semisynthetic compound vinpocetine has gained attention as a potential precision medicine for developmental and epileptic encephalopathies caused by loss‐of‐function (LoF) variants in γ‐aminobutyric acid type A (GABAA) receptor genes. As a positive allosteric modulator of GABAA receptors, case reports suggest that vinpocetine can
Cathrine E. Gjerulfsen   +15 more
wiley   +1 more source

High incidence of Y‐chromosome mosaicism in male and female individuals with mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) is an underrecognized pediatric cortical lesion associated with somatic X‐linked SLC35A2 variants in approximately 50% of individuals. The genetic etiology in individuals without detectable SLC35A2 mutations remains undefined, which limits
Erica Cecchini   +13 more
wiley   +1 more source

Colonial and gendered peace: Decolonial perspectives on peace in Nagorno‐Karabakh

open access: yesFeminist Anthropology, EarlyView.
Abstract This article critically interrogates peace processes in the aftermath of the First Nagorno‐Karabakh War by centering the lived experiences and political voices of Armenian and Azerbaijani internally displaced and refugee women, based on ethnographic fieldwork and in‐depth interviews conducted in 2019.
Ramil Zamanov
wiley   +1 more source

The Mpox contextual data specification package: a data curation toolkit to support collaborative pathogen genomic surveillance. [PDF]

open access: yesMicrob Genom
Griffiths EJ   +35 more
europepmc   +1 more source

Bioactive compounds in insects—Composition, extraction, functionality, food applications, and safety concerns

open access: yesFood Biomacromolecules, EarlyView.
This review synthesizes 94 studies (2000–2025) exploring edible insects as sustainable sources of peptides, lipids, and chitin. Utilizing “green” extraction, these bioactives offer antioxidant and antimicrobial benefits for functional foods. However, addressing safety concerns like allergenicity and heavy metals through standardized frameworks remains ...
Blessing Rachael Adeyeye   +1 more
wiley   +1 more source

Internet of Things and blockchain applications in food audit, authenticity, and traceability: A systematic review

open access: yesFood Biomacromolecules, EarlyView.
Abstract This review evaluates the integrated applications of the Internet of Things (IoT) and blockchain technologies in enhancing food audit systems, authenticity verification, and supply chain traceability, transparency, and data reliability. Following Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines, a systematic review
S. Sriranjani   +1 more
wiley   +1 more source

Food Contamination and Safety in Nigeria: A Systematic Synthesis of Heavy Metals, Microbial Pathogens, and Health Risk Metrics

open access: yesFood Safety and Health, EarlyView.
This is an infographic driver of food contaminants and health effects. ABSTRACT Food safety remains a critical challenge in Nigeria due to rapid urbanization and weak regulatory enforcement. This systematic review synthesizes empirical evidence from 2015 to 2025 to characterize food contaminant profiles and associated human health risks in Nigeria ...
Cecilia Nwadiuto Obasi   +6 more
wiley   +1 more source

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