Results 81 to 90 of about 3,585 (189)

GABAB Receptor: Structure, Biological Functions, and Therapy for Diseases

MedComm, Volume 6, Issue 5, May 2025.
Within the GABAergic system, GABABRs are potential therapeutic targets for dealing multiple metabolic and binge eating disorders and food addiction. Allosteric modulators and small peptides targeting GABABR signaling pathways may be developed as attractive drug candidates that avoid the side effects of agents that directly bind these receptors ...
Weijie Xie, Yuan Li, Xinyue Wang, Elena Blokhina, Evgeny Krupitsky, Marina Vetrova, Ji Hu, Ti‐Fei Yuan, Jue Chen, Hua Wang, Xiangfang Chen   +10 more
wiley   +1 more source

Cholinergic left-right asymmetry in the habenulo-interpeduncular pathway

, 2013
International audienceThe habenulo-interpeduncular pathway, a highly conserved cholinergic system, has emerged as a valuable model to study left-right asymmetry in the brain.
Thisse, Christine, Thisse, Bernard, Santhakumar, Kirankumar, Akitake, Courtney A., Halpern, Marnie E., Wyart, Claire, Ahn, Sang Jung, Mangin, Jean-Marie, Hong, Elim   +8 more
core   +1 more source

Diversity of GABAergic Cell Types in the Developing Mouse Interpeduncular Nucleus [PDF]

, 2020
Erilaisten hermosolujen kirjo luo perustan aivojen toiminnalle. Hermosolujen erilaisten osapopulaatioiden kehitys sekä hermosolujen erityisominaisuudet keskushermostossa ovat vielä osittain epäselviä. Näiden kehitysbiologisten asioiden ymmärtäminen voisi
Tervi, Anniina
core  

Habenula and thalamus cell transplants mediate different specific patterns of innervation in the interpeduncular nucleus

, 1992
Innervation of specific peptidergic and cholinergic compartments of the interpeduncular nucleus (IPN) was investigated using embryonic cell suspension transplants immunoreactive for substance P (SP) and ChAT. In both neonatal and adult host rats, the IPN
TC Eckenrode, F Haun, M Murray
core   +1 more source

Conserved localization of Pax6 and Pax7 transcripts in the brain of representatives of sarcopterygian vertebrates during development supports homologous brain regionalization

Frontiers in Neuroanatomy, 2014
Many of the genes involved in brain patterning during development are highly conserved in vertebrates and similarities in their expression patterns help to recognize homologous cell types or brain regions.
Nerea eMoreno, Ruth eMorona, Alberto eJoven, Sandra eBandín, Jesús M López, Agustín eGonzález   +5 more
doaj   +1 more source

Evidence for "preterminal" nicotinic receptors on GABAergic axons in the rat interpeduncular nucleus

, 1993
Presynaptic nicotinic ACh receptors (nAChRs) are abundant in the nervous system, where they are thought to regulate the release of various neurotransmitters.
C Mulle, C Lena, JP Changeux
core   +1 more source

The habenulo - interpeduncular pathway.

, 1972
Electrophysiological studies with extracellular macro- and micro-electrodes in 58 cats revealed spontaneous rhythmic oscillations in the interpeduncular nucleus, ranging tram 3 - 4 HZ to 9 - 10 Hz under different anaesthetics.
Lake, Norma.
core  

Parasagittal magnetic resonance image of the equine brain on the level of the habenulo-interpeduncular tract.

, 2019
acn: accumbens nucleus, ah: adenohypophysis, Ans: ansate sulcus, bcr: brachium of the rostral colliculus, cam: ammon’s horn, cc: corpus calosum, cdc: caudal colliculus, cf: column of fornix, cig: cingulate gyrus, cin: cingulum, cl: central lobule, cmf ...
Carola Knemeyer (6532991), Martin J. Schmidt (691108), Helmut Heinsen (386862)   +2 more
core   +1 more source

Regional expression of Pax7 in the brain of Xenopus laevis during embryonic and larval development

Frontiers in Neuroanatomy, 2013
Pax7 is a member of the highly conserved Pax gene family that is expressed in restricted zones of the central nervous system during development, being involved in early brain regionalization and the maintenance of the regional identity.
Sandra eBandín, Ruth eMorona, Nerea eMoreno, Agustín eGonzález   +3 more
doaj   +1 more source

Chemogenetic control of GABAergic neurons within the interpeduncular nucleus reveals dissociable behavioral components of the nicotine withdrawal phenotype

Neurobiology of Disease
Chronic exposure to nicotine results in the development of a dependent state such that a withdrawal syndrome is elicited upon cessation of nicotine. The interpeduncular nucleus (IPN) contains a high concentration of nicotinic acetylcholine receptors ...
Anabel M.M. Miguelez Fernández, Shana Netherton, Seshadri B. Niladhuri, Alexander C. Brown, Patricia Rivera, Kuei Y. Tseng, Christian J. Peters   +6 more
doaj   +1 more source