Results 101 to 110 of about 635,053 (187)

Improving dose delivery in non‐coplanar cranial SRS: Stereoscopic x‐ray‐guided mitigation of table walkout errors

Journal of Applied Clinical Medical Physics, EarlyView.
Purpose Linear accelerator (LINAC)‐based single‐isocenter multi‐target (SIMT) treatment has streamlined the cranial stereotactic radiosurgery (SRS) workflow. Though efficient, SIMT delivery adds additional challenges that should be considered, including increased sensitivity to rotational errors for off‐isocenter targets.
Yohan A. Walter, Philip F. Durham, Anne N. Hubbard, William E. Burrell, Hsinshun T. Wu   +4 more
wiley   +1 more source

Implementation of needle‐tracking technology for real‐time transrectal ultrasound‐guided interstitial gynecological HDR brachytherapy: A feasibility study

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To investigate the feasibility of adapting a commercial prostate biopsy system for transrectal ultrasound (TRUS)‐guided hybrid gynecological (GYN) high‐dose‐rate (HDR) brachytherapy (BT). Leveraging 3D‐TRUS and MR image fusion, the prototype system aims to improve real‐time needle placement accuracy.
Lindsey H. Bloom, Diandra Ayala‐Peacock, Rajesh Venkataraman, Brett Eckroate, Ryan Sanford, Junzo Chino, Yongbok Kim, Julie Raffi, Oana Craciunescu   +8 more
wiley   +1 more source

Machine stability and dosimetry for ultra‐high dose rate FLASH radiotherapy human clinical protocol

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The FLASH effect, induced by ultra‐high dose rate (UHDR) irradiations, offers the potential to spare normal tissue while effectively treating tumors. It is important to achieve precise and accurate dose delivery and to establish reliable detector systems, particularly for clinical trials needed to help the clinical transfer of FLASH‐
Patrik Gonçalves Jorge, Reiner Geyer, Rémy Kinj, Luis Schiappacasse, Wendy Jeanneret‐Sozzi, Jean Bourhis, Fernanda Herrera, François Bochud, Claude Bailat, Raphaël Moeckli   +9 more
wiley   +1 more source

An investigation into the feasibility and efficacy of stereotactic radiosurgery for 1–3 cm single brain lesions on the ring‐mounted Halcyon LINAC

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose An evaluation of the accuracy, safety, and efficiency of the Halcyon ring delivery system (RDS) for stereotactic radiosurgery (SRS) treatment to relatively small (1–3 cm) brain lesions. Methods After completing the extensive in‐house quality assurance checks including Winston–Lutz test and independent dose verification via MD Anderson ...
Kate Hazelwood, Shane McCarthy, Josh Misa, David Castelvetere, William St. Clair, Damodar Pokhrel   +5 more
wiley   +1 more source

Evaluating feature extraction reproducibility across image biomarker standardization initiative‐compliant radiomics platforms using a digital phantom

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The aim of this study was to thoroughly analyze the reproducibility of radiomics feature extraction across three Image Biomarker Standardization Initiative (IBSI)‐compliant platforms using a digital phantom for benchmarking. It uncovers high consistency among common features while also pointing out the necessity for standardization ...
Han‐Back Shin, Heesoon Sheen, Jang‐Hoon Oh, Young Eun Choi, Kihoon Sung, Hyun Ju Kim   +5 more
wiley   +1 more source

Enhanced analysis of gating latency in 0.35T MR‐linac through innovative time synchronization of a motion phantom and plastic scintillation detector

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study aims to evaluate how different gantry angles, breathing rates (BPM), cine image speeds, and tracking algorithms affect beam on/off latency and the subsequent impact on target dose for a 0.35T MR‐Linac with a 6 MV FFF beam.
Mateb Al Khalifa, Tianjun Ma, Haya Aljuaid, Siyong Kim, William Y. Song   +4 more
wiley   +1 more source

Beam model development and clinical experience with RadCalc for treatment plan quality assurance in online adaptive workflow with an MR‐linac

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose The aim of this work was to report on the optimization, commissioning, and validation of a beam model using a commercial independent dose verification software RadCalc version 7.2 (Lifeline Software Inc, Tyler, TX, USA), along with 4 years of experience employing RadCalc for offline and online monitor unit (MU) verification on the ...
Urszula Jelen, Zoë Moutrie, Jack D Aylward, Michael G Jameson   +3 more
wiley   +1 more source

Localization accuracy of 6‐second CBCT for lung IGRT with various breathing patterns

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose The 6‐second cone beam computed tomography (CBCT) acquisition of the Ethos HyperSight (Varian Medical Systems, Inc. Palo Alto, CA, USA) on‐board imaging system offers benefits, but could be too fast to accurately capture an average target position in a free‐breathing lung cancer patient. This study aimed to ascertain whether a 6‐second
Jihye Koo, Gage Redler, Vladimir Semenenko, Stephen A. Rosenberg, Emily Keit, Jacqueline M. Andreozzi   +5 more
wiley   +1 more source

FGF14 GAA Intronic Expansion in Unsolved Adult‐Onset Ataxia in the Care4Rare Canada Consortium

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Spinocerebellar ataxias (SCA) represent a clinically and genetically heterogeneous group of progressive neurodegenerative diseases with prominent cerebellar atrophy. Recently, a novel pathogenic repeat expansion in intron 1 of FGF14 was identified, causing adult‐onset SCA (SCA27B). We aimed to determine the proportion
Alexanne Cuillerier, Giulia F. Del Gobbo, Layla Mackay, Erika Wall, Madeline Couse, Laura M. McDonell, Mireille Cloutier, Matt C. Danzi, Jodi Warman‐Chardon, Pierre R. Bourque, Oksana Suchowersky, Alan Mears, Luke Seldenthuis, Wendy Mears, Laura Larrigan, Alexandre White‐Brown, Gerald Pfeffer, Dennis E. Bulman, David Dyment, Care4Rare Canada Consortium, Kym M. Boycott   +20 more
wiley   +1 more source

EEG Spectral Exponents and Visual Chirp Responses Mirror Anti‐Seizure Medication Load in Refractory Focal Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Quantitative markers of cortical excitability may help identify responders to anti‐seizure medications (ASMs). We studied the relationship between ASM load and two electroencephalography (EEG) markers of cortical excitability in people with refractory epilepsy. Methods We included individuals with refractory focal epilepsy undergoing
Silvano R. Gefferie, Arthur R. van Nieuw Amerongen, Gerhard H. Visser, Maeike Zijlmans, Else A. Tolner, Mark van de Ruit, Arn M. J. M. van den Maagdenberg, Roland D. Thijs   +7 more
wiley   +1 more source