Results 81 to 90 of about 147,641 (269)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Data-Driven Interpolation of Sea Level Anomalies Using Analog Data Assimilation
Remote Sensing, 2019 From the recent developments of data-driven methods as a means to better exploit large-scale observation, simulation and reanalysis datasets for solving inverse problems, this study addresses the improvement of the reconstruction of higher-resolution Sea
Redouane Lguensat +6 more
doaj +1 more source
Computer Modeling in Engineering & Sciences, 2001 The work presented provides an overview of different types of kernel interpolation used in the SPH method: conventional SPH, normalised SPH (NSPH), corrected kernel SPH (CSPH) and normalised corrected kernel SPH (NCSPH). These four methods are considered in a fully mesh-free form (using no background mesh).
Vignjevic, R., De Vuyst, T., Gourma, M.
openaire +2 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Remote Sensing, 2019 With the development of Global Navigation Satellite System (GNSS) reference station networks that provide rich data sources containing atmospheric information, the precipitable water vapor (PWV) retrieved from GNSS remote sensing has become one of the ...
Fei Yang +4 more
doaj +1 more source
Proceedings of the American Mathematical Society, 1950 where Dn(u)= 2-1's eiYu is the Dirichlet kernel and w02n+1(t) is a step function constant in the interior of the intervals [xo+kh, xo+(k+l)h] and having a jump h at the points xo+kh.' Thus W2n+1(t) is determined up to an arbitrary additive constant. It is well known that In(x; f) need not tend tof(x) even if f is everywhere continuous. S.
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source