Results 71 to 80 of about 147,641 (269)
Mapping of meteorological conditions surrounding road infrastructures is a critical tool to identify high-risk spots related to harsh weather. However, local or regional data are not always available, and researchers and authorities must rely on coarser ...
Javier López Gómez +3 more
doaj +1 more source
We treat interpolation for various logics.
Dov M. Gabbay, Karl Schlechta
openaire +2 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Dynamic Simulation of Chemical Engineering Systems by the Sequential Modular Approach [PDF]
An algorithm for dynamic simulation of chemical engineering systems, using the sequential modular approach, is proposed. The modules are independent simulators, and are integrated over a common time horizon.
Magne Hillestad, Terje Hertzberg
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
We describe a compositional approach to Craig interpolation based on the heuristic that simpler proofs of special cases are more likely to generalize. The method produces simple interpolants because it is able to summarize a large set of cases using one relatively simple fact.
Aws Albarghouthi, Kenneth L. McMillan
openaire +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Three-dimensional (3D) modeling of geological surfaces, such as coal seams and strata horizons, from sparsely sampled data collected in the field, is a crucial task in geological modeling.
Qingren Jia, Wenwen Li, Defu Che
doaj +1 more source

