Results 51 to 60 of about 182,993 (316)

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

A Simple Similarity Index for the Comparison of Remotely Sensed Time Series with Scarce Simultaneous Acquisitions

Remote Sensing, 2019
Emergence of new state-of-the-art technologies has enabled an unprecedented amount of high spatial resolution satellite data having great potential for exploitation of extracted time series for a vast range of applications.
Dominique Fasbender, Blanka Vajsová, Csaba Wirnhardt, Slavko Lemajic   +3 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

A Low Supply Voltage All-Digital Phase-Locked Loop With a Bootstrapped and Forward Interpolation Digitally Controlled Oscillator

IEEE Access, 2021
An all-digital phase-locked loop (ADPLL) with a multiphase digitally controlled oscillator (DCO) incorporating the bootstrapped and interpolated schemes is proposed in this paper.
Jen-Chieh Liu, Yu-Ping Li
doaj   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Elliptic operators of divergence type with Hölder coefficients in fractional Sobolev spaces [PDF]

Rendiconti di Matematica e delle Sue Applicazioni, 1997
This work concerns linear elliptic operators of divergence type with Hölder coefficients in spaces of type W^{1+s}_p (Ω), s ∈ [0, 1[ on a Lipschitz domain Ω. We prove that if the Laplace operator ∆ is a bicontinuous isomorphism from W^{1+s}_p (Ω) onto W^{
Stéphane Clain
doaj  

Interpolation Routines Assessment in ALS-Derived Digital Elevation Models for Forestry Applications

Remote Sensing, 2015
Airborne Laser Scanning (ALS) is capable of estimating a variety of forest parameters using different metrics extracted from the normalized heights of the point cloud using a Digital Elevation Model (DEM).
Antonio Luis Montealegre, María Teresa Lamelas, Juan de la Riva   +2 more
doaj   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

FEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo   +10 more
wiley   +1 more source

Reliability analysis of interpolation methods in travel time maps – the case of Warsaw ; Statistična analiza zanesljivosti interpolacijskih metod na karti časovne dostopnosti – primer Varšave [PDF]

Geodetski Vestnik, 2013
Describing the accessibility, by public transport, of a given place is of particular importance today. The speed and multiplicity of urban public transport have made many places far more accessible than they were at the beginning of the 20th century ...
Elzbieta Bielecka, Anna Bober
doaj