Results 61 to 70 of about 182,993 (316)

Multi-Temporal Time-Dependent Terrain Visualization through Localized Spatial Correspondence Parameterization

ISPRS International Journal of Geo-Information, 2013
Visualizing quantitative time-dependent changes in the topography requires relying on a series of discrete given multi-temporal topographic datasets that were acquired on a given time-line.
Yerach Doytsher, Sagi Dalyot
doaj   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Določitev odklonov navpičnic iz geoidnih višin : Determination of deflection of the vertical from geoid heights [PDF]

Geodetski Vestnik, 2010
Model geoida je eden od sestavnih delov državnega koordinatnega sistema. Poleg dokaj razširjenega določanja nadmorskih višin na podlagi GNSSizmere pa model geoida zagotavlja tudi kakovostnovključitev terestričnih geodetskih opazovanj v državni ...
Bojan Stopar, Marta Okorn, Miran Kuhar
doaj  

The Multivariate Theory of Connections

Mathematics, 2019
This paper extends the univariate Theory of Connections, introduced in (Mortari, 2017), to the multivariate case on rectangular domains with detailed attention to the bivariate case.
Daniele Mortari, Carl Leake
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Application of Geospatial Techniques for Groundwater Quality and Availability Assessment: A Case Study in Jaffna Peninsula, Sri Lanka

ISPRS International Journal of Geo-Information, 2018
Groundwater is one of the most important natural resources in the northern coastal belt of Sri Lanka, as there are no major water supply schemes or perennial rivers. Overexploitation, seawater intrusion and persistent pollution of this vital resource are
Kuddithamby Gunaalan, Manjula Ranagalage, M. H. J. P. Gunarathna, M. K. N. Kumari, Meththika Vithanage, Tharmalingam Srivaratharasan, Suntharalingam Saravanan, T.W.S. Warnasuriya   +7 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Practical challenges in data‐driven interpolation: Dealing with noise, enforcing stability, and computing realizations

International Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley   +1 more source

Homogeneous numerical cubature formulas of interpolatory type

Journal of Numerical Analysis and Approximation Theory, 2002
In this paper we construct homogeneous numerical cubature formulas based on some numerical multivariate interpolation schemes.
Gheorghe Coman, Maria Solomon
doaj   +2 more sources