Results 91 to 100 of about 2,794,459 (245)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Perception, aperception et conscience chez Leibniz [PDF]
, 2014 Cet article propose une interprétation de certains passages qui posent un problème de cohérence dans la théorie leibnizienne de la perception et de l’aperception.
Charbonneau, Antoine
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
La préciosité: de l’éclat des salons aux précieuses ridicules [PDF]
, 2015 Le motif fondamental qui m’a conduite à choisir la préciosité comme thème de travail de fin d’études a été ceci: la double interprétation de la préciosité comme un phénomène, depuis son époque jusqu’à nos jours, tantôt positif comme négatif.
Antón Martínez, Azucena
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Etude expérimentale et numérique de la dissolution d’un polluant hydrocarboné dans un milieu poreux hétérogène [PDF]
, 2015 Le travail présenté traite de la dissolution d'un solvant partiellement miscible dans l'eau en milieu poreux hétérogène saturé. Une étude expérimentale réalisée à la fois sur des milieux poreux microscopiquement et macroscopiquement hétérogènes met en ...
AHMADI-SENICHAULT, Azita +2 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
, 2011 International audienceCompte rendu de: Racines. Patrimoine - Gestion - Interprétation. Revue annuelle de l'Office du Parc National du Tassili.
Le Quellec, Jean-Loïc
core +2 more sources