Results 111 to 120 of about 2,751,409 (242)

Interprétation littéraire et sciences cognitives (dir. Françoise Lavocat, 2016)

open access: yes, 2022
International audienceReview of the collective volume Interprétation littéraire et sciences cognitives (ed. François Lavocat, Hermann, 2016).Recension de l'ouvrage collectif Interprétation littéraire et sciences cognitives, textes réunis et présentés par
Raffard, Manon
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Interprétation motivationniste de l'image publicitaire

open access: yes, 1973
Victoroff David. Interprétation motivationniste de l'image publicitaire. In: Bulletin de psychologie, tome 26 n°307, 1973. pp.
Victoroff, David
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Une « forme » pour la sémiotique discursive : la théorie des instances énonçantes

open access: yesActes Sémiotiques
Pour « l’instance de réception » du sens que nous sommes, tout procès sémiosique, tout ensemble signifiant suppose une « instance énonçante » qui se trouve à son origine et qui « énonce », à travers ce qu’elle signifie, un rapport au monde, le sien ou ...
Ahmed Kharbouch
doaj   +1 more source

Signe, déchiffrement, interprétation

open access: yes, 2003
SIGNE, DÉCHIFFREMENT, INTERPRÉTATION Recherche interdisciplinaire sur le XIXe siècle avec la collaboration de l’équipe « Littérature et herméneutique » de Toulouse le Mirail, du « Centre de poétique et génétique romanesques » de Paris III, de l’

core  

Karst et photo-interprétation en Andalousie

open access: yes, 1976
Nicod Jean. Karst et photo-interprétation en Andalousie. In: Méditerranée, deuxième série, tome 27, 4-1976. pp.
Jean Nicod, Nicod, Jean
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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