Results 121 to 130 of about 424,704 (329)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

AUNET (Attention-Based Unified Network): Leveraging Attention-Based N-BEATS for Enhanced Univariate Time Series Forecasting

open access: yesIEEE Access
Univariate time series forecasting is pivotal in domains such as climate modeling, finance, and healthcare, where both short-term precision and long-term reliability are essential.
Adria Binte Habib   +2 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

On the use of kolmogorov–arnold networks for adapting wind numerical weather forecasts with explainability and interpretability: application to madeira international airport

open access: yesEnvironmental Research Communications
This study examines the application of machine learning to enhance wind nowcasting by using a Kolmogorov-Arnold Network model to improve predictions from the Global Forecast System at Madeira International Airport, a site affected by complex terrain. The
Décio Alves   +3 more
doaj   +1 more source

Class Activation Map Guided Backpropagation for Discriminative Explanations

open access: yesApplied Sciences
The interpretability of neural networks has garnered significant attention. In the domain of computer vision, gradient-based feature attribution techniques like RectGrad have been proposed to utilize saliency maps to demonstrate feature contributions to ...
Yongjie Liu   +4 more
doaj   +1 more source

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