Results 121 to 130 of about 244,685 (311)

An Interpretation Of Rawls’ “Kantian Interpretation”

open access: yesCon-textos Kantianos: International Journal of Philosophy, 2015
Calling Kant a liberal philosopher requires important qualifications. Much like his theoretical philosophy, his political transcendentalism was and remains a great enterprise of navigating between the extremes of liberalism and conservatism, of balancing the “empirical” and the “pure” in human society, as well as in human mind.
openaire   +3 more sources

The many faces of interpretability

open access: yes, 2008
. In this paper we discus work in progress on interpretability logics. We show how semantical considerations have allowed us to formulate non-trivial principles about formalized interpretability.
J. J. Joosten, E. Goris
core  

Extension & Interpretability [PDF]

open access: yes, 2015
In this paper we study the combined structure of the relations of theory-extension and interpretability between theories for the case of finitely axiomatised theories. We focus on two main questions. The first is the matter of definability of salient
Visser, A., Visser, Albert
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

An Interpretable Transformer Model for Operational Flare Forecasting

open access: yesProceedings of the International Florida Artificial Intelligence Research Society Conference
Interpretable machine learning tools including LIME (Local Interpretable Model-agnostic Explanations) and ALE (Accumulated Local Effects) are incorporated into a transformer-based deep learning model, named SolarFlareNet, to interpret the predictions ...
Yasser Abduallah   +2 more
doaj   +1 more source

Bi-Unary Interpretability Logic

open access: yes, 1990
Introduction In recent years several modal systems have been introduced to study the relation of relative interpretability between arithmetical theories.
Maarten De Rijke
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

IRGL-RRI: interpretable graph representation learning for plant RNA–RNA interaction discovery

open access: yesFrontiers in Plant Science
Plant RNAs are crucial for plant gene expression and protein synthesis. They modulate the spatial structure of themselves and associated molecules, thereby influencing transcription, translation and gene expression regulation.
Qingquan Liao   +6 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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