Results 101 to 110 of about 424,704 (329)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A review of general pain measurement tools and instruments for consideration of use in COPD clinical practice

International Journal of COPD, 2017
Alisha Maree Johnson,1 Sheree MS Smith1,2 1School of Nursing and Midwifery, Western Sydney University, Penrith, 2Respiratory, Sleep, and Environmental Health Research Academic Unit, Liverpool Hospital, Liverpool, NSW, Australia Background: The ...
Johnson AM, Smith SMS
doaj  

Peer Review #1 of "Interpretable deep learning for the prediction of ICU admission likelihood and mortality of COVID-19 patients (v0.1)"

, 2022
Nazir Corresp, Hyacinth Kwadwo, Ampadu Equal, Amril Nazir, Ampadu Kwadwo, H Abdi, L Williams, I Bogoch, A Watts, A Thomas-Bachli, C Huber, M Kraemer, K Khan, F Bozkurt, M Tercan, G Patmano, T Tanrverdi, H Demir, U Yurekli, N Chawla, K Bowyer, L Hall, W Kegelmeyer, S Dahan, G Segal, I Katz, T Hellou, M Tietel, G Bryk, H Amital, Y Shoenfeld, A Dagan, M Dinevari, M Somi, E Majd, M Farhangi, Z Nikniaz, F Fernandes, T De Oliveira, C Teixeira, A De Moraes Batista, G Dalla Costa, A Chiavegatto Filho, F Gerayeli, S Milne, C Cheung, X Li, C Yang, A Tam, L Choi, A Bae, D Sin, M Goic, M Bozanic-Leal, M Badal, L Basso, D Graziani, J Soriano, D Rio-Bermudez, D Morena, T Daz, M Castillo, M Alonso, J Ancochea, S Lumbreras, J Izquierdo, H He, Y Bai, E Garcia, S Li, A Hyvarinen, K Ikemura, E Bellin, Y Yagi, H Billett, M Saada, K Simone, L Stahl, J Szymanski, D Goldstein, M Gil, K Leung, J Wu, D Liu, G Leung, Q Li, X Guan, P Wu, X Wang, L Zhou, Y Tong, R Ren, K Leung, E Lau, J Wong, X Li, P Ge, J Zhu, H Li, J Graham   +99 more
openalex   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Interpreting national hip fracture data [PDF]

, 2014
Tim Chesser, A. John Timperley
openalex   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Study on the Compressive Strength Predicting of Steel Fiber Reinforced Concrete Based on an Interpretable Deep Learning Method

Applied Sciences
Steel fiber reinforced concrete (SFRC) exhibits excellent material enhancement and toughening properties. It is widely used in applications such as airport runways, highway pavements, and bridge deck overlays. In order to predict the compressive strength
Huiming Wang, Jie Lin, Shengpin Guo
doaj   +1 more source

Report on Transformers interpretability for Natural Language Processing: A case study on Technical Debt classification

, 2023
Karthik Shivashankar
openalex   +1 more source

Statutory Interpretation

, 2006
Regsgeleerdheid ; Privaatreg ; Please help us populate SUNScholar with the post print version of this article.
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source