Results 61 to 70 of about 1,650,720 (280)

Intersection Homology. General perversities and topological invariance

open access: yes, 2019
Topological invariance of the intersection homology of a pseudomanifold without codimension one strata, proven by Goresky and MacPherson, is one of the main features of this homology. This property is true for codimension-dependent perversities with some
Chataur, David   +2 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

A Route Planning and Traffic Control Model for Autonomous Intersections by Minimizing Conflict Zones

open access: yesIEEE Access, 2023
Most existing studies on autonomous intersection management (AIM) primarily focus on modeling and resolving conflicts between vehicles within an intersection, assuming predetermined routes of the autonomous vehicles (AVs) as exogenous inputs ...
Yang Liu, Kejun Long, Wei Wu
doaj   +1 more source

Transferable Pedestrian Motion Prediction Models at Intersections

open access: yes, 2019
One desirable capability of autonomous cars is to accurately predict the pedestrian motion near intersections for safe and efficient trajectory planning.
Habibi, Golnaz   +2 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

INFLUENCE OF PARAMETERS OF THE TRAFFIC- LIGHT REGULATION CYCLE ON THE ROAD CAPACITY OF REGULATED INTERSECTIONS

open access: yesВестник СибАДИ, 2019
Introduction. Road capacity refers to the main indicators, characterizing the working conditions of streets and highways. For the street capacity as a whole the minimum value of a certain section is taken, which includes adjustable intersections in one ...
K. Isakov   +3 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

The dual regulatory role of METTL14-mediated m6A modification in tumorigenesis and its underlying mechanisms

open access: yesFrontiers in Oncology
N6-methyladenosine (m6A), as the most abundant RNA epitranscriptional modification in eukaryotes, its key component of the methyltransferase complex, METTL14, not only cooperates in catalyzing m6A deposition but also has functions independent of ...
Yulan Yang   +3 more
doaj   +1 more source

L'intertextualité dans le Roman "Nisf Majhoul" (Moitié Inconnu) de Gamal Al- Jaziri [PDF]

open access: yesMaǧallaẗ Kulliyyaẗ Al-ādāb Ǧāmiʿaẗ Būrsaʿīd
La recherche des sources et l’étude des influences d’écrivain en écrivain occupent aujourdʼhui , dans les études littéraires , une place considérable .
Mohamed Elsayed Mohamed Elsawy
doaj   +1 more source

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