Results 41 to 50 of about 596,231 (252)
A case report of onycholemmal carcinoma in a 61-year-old Chinese male
JPRAS OpenOnycholemmal carcinoma is characterized as a slowly progressing malignant tumor originating from the epithelium of the nail bed. A limited number of cases have been documented in the English literature.
Xiaoshuang Chen, Song Wu, Xianju Zhang
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
At the intersection of disability and masculinity: Exploring gender and bodily difference in India [PDF]
, 2011 This is the accepted version of the following article: STAPLES, J. (2011), At the intersection of disability and masculinity: exploring gender and bodily difference in India. Journal of the Royal Anthropological Institute, 17: 545–562.
Staples, J, JAMES STAPLES
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Вестник СибАДИ, 2019 Introduction. Road capacity refers to the main indicators, characterizing the working conditions of streets and highways. For the street capacity as a whole the minimum value of a certain section is taken, which includes adjustable intersections in one ...
K. Isakov +3 more
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
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Frontiers in OncologyN6-methyladenosine (m6A), as the most abundant RNA epitranscriptional modification in eukaryotes, its key component of the methyltransferase complex, METTL14, not only cooperates in catalyzing m6A deposition but also has functions independent of ...
Yulan Yang +3 more
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L'intertextualité dans le Roman "Nisf Majhoul" (Moitié Inconnu) de Gamal Al- Jaziri [PDF]
Maǧallaẗ Kulliyyaẗ Al-ādāb Ǧāmiʿaẗ BūrsaʿīdLa recherche des sources et l’étude des influences d’écrivain en écrivain occupent aujourdʼhui , dans les études littéraires , une place considérable .
Mohamed Elsayed Mohamed Elsawy
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