Results 41 to 50 of about 1,650,720 (280)

Sustainable leadership pre- and within the 21st century [PDF]

Environmental Economics, 2017
This paper reviews literature on sustainable leadership pre- and within the 21st century, using the following nuances: (1) selected dynamics attributable to socio-demographics, (2) implications and barriers that skew gender and leadership bias, and (3 ...
Bloodless Dzwairo, Ntombenhle Nombela, Manoshni Perumal   +2 more
doaj   +1 more source

Road Safety Audit for the Intersection of US 59 and IA 9 in Osceola County, Iowa Final Report, March 2012 [PDF]

, 2012
The Iowa Department of Transportation (DOT) requested a road safety audit (RSA) of the US 59/IA 9 intersection in northwestern Iowa, just south of the Minnesota border, to assess intersection environmental issues and crash history and recommend ...

core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Evaluation of reports received on a digital platform for monitoring and self-care of individuals facing the COVID-19 pandemic in Brazil: Contributions to public health

Clinical Epidemiology and Global Health
Objectives: To evaluate the contribution of the digital platform “Meu Diário de Quarentena (MDQ)'' or My Quarantine Diary concerning the monitoring and self-care of individuals with COVID-19 in Brazil.
Luiz Ricardo Albano dos Santos, Luana Michelly Aparecida Costa dos Santos, Guilherme José Aguilar, Wilbert Dener Lemos Costa, Dantony de Castro Barros Donato, Valdes Roberto Bollela, Alan Maicon de Oliveira   +6 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Intersectional Strategies for Targeting Amacrine and Ganglion Cell Types in the Mouse Retina

Frontiers in Neural Circuits, 2018
The mammalian retina harbors over 100 different cell types. To understand how retinal circuits work, it is essential to systematically access each type. A widely used approach for achieving targeted transgene expression exploits promoter-driven Cre lines.
Andrew Jo, Jian Xu, Sercan Deniz, Suraj Cherian, Steven H. DeVries, Steven H. DeVries, Yongling Zhu, Yongling Zhu   +7 more
doaj   +1 more source

The Spatial Different Order Derivative Method of Gravity and Magnetic Anomalies for Source Distribution Inversion

Remote Sensing, 2021
Gravity and magnetic measurements are common remote sensing strategies to obtain the property change of observed targets. Nowadays, the characteristic value of the derivatives of gravity and magnetic anomalies is commonly used to detect the source ...
Yanbo Ming, Guoqing Ma, Lili Li, Jiangtao Han, Taihan Wang   +4 more
doaj   +1 more source

Complete intersection vanishing ideals on degenerate tori over finite fields

, 2012
We study the complete intersection property and the algebraic invariants (index of regularity, degree) of vanishing ideals on degenerate tori over finite fields.
Lopez, Hiram H., Villarreal, Rafael H., Zarate, Leticia   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Saturation flow versus green time at two‐stage signal controlled intersections [PDF]

Transport, 2009
Intersections are the key components of road networks considerably affecting capacity. As flow levels and experience have increased over the years, methods and means have been developed to cope with growing demand for traffic at road junctions.
Ahmed Boumediene, Kouider Brahimi, Noreddine Belguesmia, Khaled Bouakkaz   +3 more
doaj   +1 more source