Results 51 to 60 of about 476,385 (316)
Decoding TGR5: A comprehensive review of its impact on cerebral diseases
Pharmacological ResearchCurrently, unraveling the enigmatic realm of drug targets for cerebral disorders poses a formidable challenge. Takeda G protein-coupled receptor 5 (TGR5), also known as G protein-coupled bile acid receptor 1, is a specific bile acid receptor.
Zehan Zhang +9 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Intersection Safety using Lidar and Stereo Vision sensors [PDF]
, 2011 International audienceIn this paper, we describe our approach for intersection safety developed in the scope of the European project INTERSAFE-2. A complete solution for the safety problem including the tasks of perception and risk assessment using on ...
Michel Parent +17 more
core +1 more source
The Optimal Allocation of the Library Space to Books Using Cuckoo Algorithm
تحقیقات اطلاعرسانی و کتابخانههای عمومی, 2015 Purpose: The goal of this research is to describe how we can arrange the books in the shelves such that leads to minimization of the movement of the clients in the library and reduction of restrictions on the number and volume of each type of book ...
houshmand moradveisi +1 more
doaj
Frontiers in Public HealthThe accelerating demographic transition has brought the mental health of older adults to the forefront of public health concerns. Middle-aged and older adults (aged 50–69 years), often described as the “young-old,” are particularly vulnerable to early ...
Han Zhang, Siqi Zhu
doaj +1 more source
Intersectional Strategies for Targeting Amacrine and Ganglion Cell Types in the Mouse Retina
Frontiers in Neural Circuits, 2018 The mammalian retina harbors over 100 different cell types. To understand how retinal circuits work, it is essential to systematically access each type. A widely used approach for achieving targeted transgene expression exploits promoter-driven Cre lines.
Andrew Jo +7 more
doaj +1 more source
Remote Sensing, 2021 Gravity and magnetic measurements are common remote sensing strategies to obtain the property change of observed targets. Nowadays, the characteristic value of the derivatives of gravity and magnetic anomalies is commonly used to detect the source ...
Yanbo Ming +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Saturation flow versus green time at two‐stage signal controlled intersections [PDF]
Transport, 2009 Intersections are the key components of road networks considerably affecting capacity. As flow levels and experience have increased over the years, methods and means have been developed to cope with growing demand for traffic at road junctions.
Ahmed Boumediene +3 more
doaj +1 more source
Data Delivery Delay Reduction for VANETs on Bi-Directional Roadway
IEEE Access, 2016 In this paper, we investigate the data delivery delay from source to destination for VANETs on bi-directional roadways. The topology includes bi-directional roadways, left-turn lane, straight through lane, right-turn lane with traffic lights deployed at ...
Chang Guo +3 more
doaj +1 more source