Results 31 to 40 of about 458,373 (267)

Tridiagonal Interval Matrix: Exploring New Perspectives and Application

Science and Technology Indonesia
Tridiagonal interval matrices are relevant in diverse applications, especially in dealing with parameter estimation, optimization and circuit analysis uncertainties.
Sivakumar Thirupathi, Nirmala Thamaraiselvan   +1 more
doaj   +3 more sources

Matrix Games with Interval-Valued 2-Tuple Linguistic Information

Games, 2018
In this paper, a two-player constant-sum interval-valued 2-tuple linguistic matrix game is construed. The value of a linguistic matrix game is proven as a non-decreasing function of the linguistic values in the payoffs, and, hence, a pair of auxiliary ...
Anjali Singh, Anjana Gupta
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Efficient Implementation of Interval Matrix Multiplication [PDF]

, 2012
The straightforward implementation of interval matrix product suf- fers from poor efficiency, far from the performances of highly optimized floating-point implementations. In this paper, we show how to reduce the interval matrix multiplication to 9 floating-point matrix products - for performance issues - without sacrificing the quality of the result ...
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

On a Matrix over NC and Multiset NC Semigroups

Journal of Mathematics, 2022
In this paper, we define a matrix over neutrosophic components (NCs), which was built using the four different intervals 0,1,0,1,0,1, and 0,1. This definition was made clear by introducing some examples.
Mohammed A. Saleem, Mohamed Abdalla, A. Elrawy   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Inverse interval matrix: A survey [PDF]

The Electronic Journal of Linear Algebra, 2011
Results on the inverse interval matrix, both theoretical and computational, are surveyed. Described are, among others, formulae for the inverse interval matrix, NP-hardness of its computation, various classes of interval matrices for which the inverse can be given explicitly, and closed-form formulae for an enclosure of the inverse. 1. Introduction. In
Jiri Rohn, Raena Farhadsefat
openaire   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source