Results 41 to 50 of about 2,941,748 (302)

Efficient Implementation of Interval Matrix Multiplication [PDF]

, 2012
The straightforward implementation of interval matrix product suf- fers from poor efficiency, far from the performances of highly optimized floating-point implementations. In this paper, we show how to reduce the interval matrix multiplication to 9 floating-point matrix products - for performance issues - without sacrificing the quality of the result ...
openaire   +3 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Generalized difference interval matrix and some interval matrix calculations

, 2023
Bu tez dört bölümden oluşmaktadır. Birinci bölümde, interval sayılara neden ihtiyaç duyulduğu ve ortaya çıkışı ile ilgili açıklamalar verilmiştir. İkinci bölümde, interval sayılarla ilgili yapılan çalışmalar ve tezimizde ihtiyaç duyulan temel tanım ve ...
Zararsız, Zarife, Ceylan, Meliha
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Reduced-Order and Full-Order Interval Observers Design for Discrete-Time System

IEEE Access, 2020
In this paper, the design of reduced-order and full-order interval observers for discrete-time system is investigated. First, the original system is transformed into a descriptor system with the ability to estimate the unknown noise of sensors.
Weijie Ren, Renyang You, Wei Yu, Shenghui Guo   +3 more
doaj   +1 more source

An interval Kalman filter enhanced by lowering the covariance matrix upper bound

International Journal of Applied Mathematics and Computer Science, 2021
This paper proposes a variance upper bound based interval Kalman filter that enhances the interval Kalman filter based on the same principle proposed by Tran et al. (2017) for uncertain discrete time linear models.
Tran Tuan Anh, Jauberthie Carine, Trave-Massuyés Louise, Lu Quoc Hung   +3 more
doaj   +1 more source

Inverse interval matrix: A survey [PDF]

The Electronic Journal of Linear Algebra, 2011
Results on the inverse interval matrix, both theoretical and computational, are surveyed. Described are, among others, formulae for the inverse interval matrix, NP-hardness of its computation, various classes of interval matrices for which the inverse can be given explicitly, and closed-form formulae for an enclosure of the inverse. 1. Introduction. In
Jiri Rohn, Raena Farhadsefat
openaire   +1 more source

Dynamics of non-classical interval exchanges [PDF]

, 2010
A natural generalization of interval exchange maps are linear involutions, first introduced by Danthony and Nogueira [Measured foliations on non-orientable surfaces. Ann. Sci. Éc. Norm. Supér. (4) 26(6) (1993), 645–664].
Gadre, Vaibhav, Gadre, Vaibhav H., Gadre, Vaibhav S., VAIBHAV S. GADRE   +3 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source