Results 61 to 70 of about 426,364 (268)
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Interval-constrained matrix balancing
Linear Algebra and its Applications, 1991 The following two problems are studied: 1. Given a nonnegative (m,n)-matrix \(A=(a_{ij})\) and positive vectors u, v; determine a `nearby' nonnegative (m,n)-matrix \(X=(x_{ij})\) such that \(\sum_{j}x_{ij}=u_ i\), \(i=1,...,m\), \(\sum_{i}x_{ij}=v_ j\), \(j=1,...,n\) and \(x_{ij}>0\) only if \(a_{ij}>0.\) 2.
Censor, Yair +3 more
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
A Mixed H2/H∞ Control Method for UAV Based on T-S Fuzzy Model
Kongzhi Yu Xinxi Jishu, 2018 A mixed H2/H∞ control strategy was proposed in this paper to achieve a stable tracking trajectory of the UAV(unmanned aerial vehicle). Firstly, the quadrotor UAV was divided into three subsystems: the altitude, the position and the attitude. By selecting
SUN Miaoping, DING Nan, NIAN Xiaohong
doaj
Scientific Reports, 2022 An improved interval-valued intuitionistic fuzzy multi-attribute group decision-making method considering the risk preference of decision-makers is proposed to solve the multi-attribute group decision-making problem with interval-valued intuitionistic ...
Sha Fu, Ye-zhi Xiao, Hang-jun Zhou
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Interval Matrix Vector Calculator—The iMVC 1.0
, 2002 The article presents a computer dialogue system for calculating intervals elementary arithmetic operations. In particular, it has a set of functions for checking practical regularity and practical stability of a square interval matrix. This software is a part of an active learning approach.
Bulgak, Ayşe, Eminov, Diliaver
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Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
On the Interval Generalized Coupled Matrix Equations
The Electronic Journal of Linear Algebra, 2018 In this work, the interval generalized coupled matrix equations \begin{equation*} \sum_{j=1}^{p}{{\bf{A}}_{ij}X_{j}}+\sum_{k=1}^{q}{Y_{k}{\bf{B}}_{ik}}={\bf{C}}_{i}, \qquad i=1,\ldots,p+q, \end{equation*} are studied in which ${\bf{A}}_{ij}$, ${\bf{B}}_{ik}$ and ${\bf{C}}_{i}$ are known real interval matrices, while $X_{j}$ and $Y_{k}$ are the unknown ...
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Two Iterative Methods for Solving Linear Interval Systems
Applied Computational Intelligence and Soft Computing, 2018 Conjugate gradient is an iterative method that solves a linear system Ax=b, where A is a positive definite matrix. We present this new iterative method for solving linear interval systems Ãx̃=b̃, where à is a diagonally dominant interval matrix, as ...
Esmaeil Siahlooei +1 more
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