Results 181 to 190 of about 52,505 (294)

Impact of Habitual Flexion on Bone Formation After Spinal Fusion Surgery: An In Silico Study

JOR SPINE, Volume 8, Issue 3, September 2025.
Lumbar spinal fusion is an effective treatment for spinal conditions, but non‐union remains a challenge due to unfavorable mechanical signals at the fusion site. This study used a computational model to investigate how habitual flexion loading affects bone fusion, finding that hybrid (compression + flexion) loading led to greater bone formation ...
Siddarth Ananth Swaminathan, Nima Taheri, Luis Becker, Matthias Pumberger, Hendrik Schmidt, Sara Checa   +5 more
wiley   +1 more source

Intervertebral disc degeneration, age, and sex affect the range of motion of the cervical spine. [PDF]

Sci Rep
Liebsch C, Greiner-Perth AK, Vogt M, Vieres V, Jonas R, Kienle A, Wilke HJ.   +6 more
europepmc   +1 more source

TRIM29 alleviates intervertebral disc degeneration through the PI3K/AKT/mTOR pathway. [PDF]

Sci Rep
Yang Q, Feng J, Xu H, Kang T, Wei Q, Jiang H.   +5 more
europepmc   +1 more source

Calcification of Intervertebral Discs in the Dachshund

, 1991
Øyvind Stigen
openalex   +2 more sources

Chondrodystrophic Dogs as a Preclinical Large Animal Model of Discogenic Back Pain

JOR SPINE, Volume 8, Issue 3, September 2025.
This study aims to validate an underutilized canine preclinical model of discogenic back pain model by deep phenotyping several structural and pain associated outcomes with novel findings in the areas of RNA sequencing and whole patch clamp of canine dorsal root ganglion neurons.
Mary K. Heimann, Shirley N. Tang, Gilian Gunsch, Kyle Kuchynsky, Brett Klamer, Fangli Zhao, Megan Co, Maciej Pietrzak, Justin Richards, Jake Klausner, Adam Smith, Kaitlyn Cimney, Sara McBride‐Gagyi, Brad Youngblood, Kara Corps, Candice Askwith, Benjamin A. Walter, Sarah A. Moore, Devina Purmessur   +18 more
wiley   +1 more source

Mechanisms and Therapeutic Strategies of Macrophage Polarization in Intervertebral Disc Degeneration. [PDF]

JOR Spine
Zheng K, Wang S, Deng M, Luo Y, Li W, Zeng L, Wang Y.   +6 more
europepmc   +1 more source

Usefulness of Computed Tomography after Myelography for Surgery on Dogs with Cervical Intervertebral Disc Protrusion.

, 1994
Yasushi Hara, M Tagawa, H Ejima, Hiromitsu Orima, Michio Fujita   +4 more
openalex   +2 more sources

Mechanistic Interactions Driving Nucleus Pulposus Cell Senescence in Intervertebral Disc Degeneration: A Multi‐Axial Perspective of Mechanical, Immune, and Metabolic Pathways

JOR SPINE, Volume 8, Issue 3, September 2025.
The senescence of NPCs is at the heart of the pathogenesis of intervertebral disc degeneration (IVDD), which causes low back discomfort. ABSTRACT Background The senescence of nucleus pulposus cells (NPCs) at the heart of the pathogenesis of intervertebral disc degeneration (IVDD), which causes low back pain.
Yunbo Yang, Haoming Li, Junhui Zuo, Fei Lei   +3 more
wiley   +1 more source

Association of dyslipidemia with intervertebral disc degeneration: a case-control study. [PDF]

Eur J Med Res
Tan B, Xiang S, Zheng Y, Ouyang J, Zhou N.   +4 more
europepmc   +1 more source

Development and Validation of a Machine Learning‐Based Online Prognostic Model for Cervical Spondylosis Patients After Anterior Cervical Discectomy and Fusion: A Multicenter Study

JOR SPINE, Volume 8, Issue 3, September 2025.
This was a multi‐center, retrospective, and prospective study based on multiple machine learning algorithms. This online predictive tool offers a robust framework for personalized postoperative management in CS patients, potentially improving clinical outcomes.
Sitan Feng, Shengsheng Huang, Zhongxian Zhou, Bin Zhang, Chengqian Huang, Tianyou Chen, Chenxing Zhou, Shaofeng Wu, Jichong Zhu, Jiarui Chen, Jiang Xue, Xinli Zhan, Chong Liu   +12 more
wiley   +1 more source