Results 1 to 10 of about 37,526 (187)
Frontiers in Pharmacology, 2023 Apoptosis and extracellular matrix degradation of the nucleus pulposus are the main initiators of intervertebral disc degeneration (IVDD) and can be explained by endoplasmic reticulum (ER) stress.
Yan Chen +10 more
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The role of ageing and oxidative stress in intervertebral disc degeneration
Frontiers in Molecular Biosciences, 2022 Intervertebral disc degeneration (IDD) is the primary cause of intervertebral disc (IVD) disease. With the increased ageing of society, an increasing number of patients are plagued by intervertebral disc disease. Ageing not only accelerates the decreased
Pengfei Wen +5 more
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Protective role of the alpha-1-antitrypsin in intervertebral disc degeneration
Journal of Orthopaedic Surgery and Research, 2021 Background Intervertebral disc degeneration is a complex disease with high prevalence. It suggests that cell death, senescence, and extracellular matrix degradation are involved in the pathogenesis. Alpha-1 antitrypsin (AAT), a serine protease inhibitor,
Weikun Liu, Yanfu Wang
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Application study of 3D LAVA-Flex on lumbar intervertebral disc degeneration
European Journal of Medical Research, 2021 Background Degeneration of the intervertebral discs are very common diseases, indicating the specific or malignant changes in intervertebral disc component, structure and function.
Tiefang Liu +6 more
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Identification of Key Modules and Hub Genes of Annulus Fibrosus in Intervertebral Disc Degeneration
Frontiers in Genetics, 2021 Background: Intervertebral disc degeneration impairs the quality of patients lives. Even though there has been development of many therapeutic strategies, most of them remain unsatisfactory due to the limited understanding of the mechanisms that underlie
Hantao Wang +5 more
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陆军军医大学学报, 2023 Objective To explore the role and possible mechanism of lysyl oxidase (LOX) in age-related degeneration of intervertebral disc. Methods Six SD rats, aged of 2, 8 and 20 months respectively, were subjected, and then underwent intervertebral disc MRI and X-
LI Jianmin +3 more
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Exosomes and exosomal miRNAs: A new therapy for intervertebral disc degeneration
Frontiers in Pharmacology, 2022 Low back pain has been found as a major cause of global disease burden and disability. Intervertebral disc degeneration is recognized as the vital factor causing low back pain.
Zhichao Li +5 more
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Frontiers in Bioengineering and Biotechnology, 2022 Intervertebral disc (IVD) degeneration (IDD) is the most universal pathogenesis of low back pain (LBP), a prevalent and costly medical problem across the world.
Zongtai Liu, Changfeng Fu
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Prague Medical Report, 2022 Intervertebral disc degeneration is a pathological condition associated with the intervertebral disc and is related to functional alterations in the human body.
Nicole Barbosa Bettiol +9 more
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Effect of sIL-13Rα2-Fc on the progression of rat tail intervertebral disc degeneration
Journal of Orthopaedic Surgery and Research, 2019 Background The incidence of degenerative disc disease caused by intervertebral disc injury is increasing annually, seriously affecting the quality of life of patients and increasing the disease burden on society.
Xin Wang +7 more
doaj +1 more source