Results 41 to 50 of about 413,430 (258)
IntroductionLow back pain (LBP) was commonly induced by intervertebral disc degeneration (IVDD), which is accompanied by the loss of disc height and osteophyte generation.
Chen Chen +8 more
doaj +1 more source
Intervertebral disc characterization by shear wave elastography: an in-vitro preliminary study [PDF]
Patient-specific numerical simulation of the spine is a useful tool both in clinic and research. While geometrical personalization of the spine is no more an issue, thanks to recent technological advances, non-invasive personalization of soft tissue’s ...
VERGARI, Claudio +7 more
core +1 more source
Objective: Intervertebral disc degeneration was characterized with aberrant intervertebral disc nucleus pulposus cells apoptosis. MiR-532 was reported to be up-regulated in the patients with intervertebral disc degeneration.
Zeyu Sun +3 more
doaj +1 more source
Cell therapy for the degenerating intervertebral disc [PDF]
Spinal conditions related to intervertebral disc (IVD) degeneration cost billions of dollars in the US annually. Despite the prevalence and soaring cost, there is no specific treatment that restores the physiological function of the diseased IVD. Thus, it is vital to develop new treatment strategies to repair the degenerating IVD.
Wei Tong +10 more
openaire +2 more sources
Role of Necroptosis in Intervertebral Disc Degeneration
Apoptosis has historically been considered the primary form of programmed cell death (PCD) and is responsible for regulating cellular processes during development, homeostasis, and disease. Conversely, necrosis was considered uncontrolled and unregulated.
Md Abdul Khaleque +5 more
openaire +2 more sources
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li +4 more
wiley +1 more source
Intervertebral discs have long been considered to lack neural innervation. However, recent studies have revealed that intervertebral disc degeneration is accompanied by marked pathological nerve invasion.
Ang Li +6 more
doaj +1 more source
Cervical intervertebral disc degeneration and dizziness
Clinical studies have found that patients withcervical degenerative disease are usually accompanied by dizziness. Anterior cervical surgery can eliminate not only chronic neck pain, cervical radiculopathy or myelopathy, but also dizziness. Immunohistochemical studies show that a large number of mechanoreceptors, especially Ruffini corpuscles, are ...
Liu, Tang-Hua +2 more
openaire +2 more sources
Cumulative occupational lumbar load and lumbar disc disease : results of a German multi-center case-control study (EPILIFT) [PDF]
Background The to date evidence for a dose-response relationship between physical workload and the development of lumbar disc diseases is limited. We therefore investigated the possible etiologic relevance of cumulative occupational lumbar load to lumbar
Grifka, Joachim +46 more
core +2 more sources
Background Intervertebral disc degeneration and sarcopenia are both age-related diseases without effective treatments. Their comorbidities may worsen the prognosis, and further studies on interaction and therapy are needed.
Hui Yuan +9 more
doaj +1 more source

