Breaking the degenerative triad: Microenvironment reprogramming biomaterials for intervertebral disc regeneration. [PDF]
Zhao X +15 more
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Methodological Concerns Regarding the Claimed Causal Role of S100A12 in Intervertebral Disc Degeneration and Osteoporosis [Letter]. [PDF]
Tian W, Li Z, Wang B.
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Development and Histopathological Validation of a Novel Unilateral Three-Level Lumbar Artery Ligation Model of Progressive Intervertebral Disc Degeneration. [PDF]
Ugur F +4 more
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Gut-Intervertebral Disc Axis: Gut Microbiome-Driven Immune-Metabolic Imbalance and Intervertebral Disc Degeneration. [PDF]
Cui X, Du W.
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Cationized gelatin nanosphere-mediated release-controlled RNA interference targeting mTORC1 protects against intervertebral disc degeneration. [PDF]
Hiranaka Y +13 more
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Genetics of intervertebral disc disease: A review
Clinical Anatomy, 2021AbstractIntervertebral disc disease (IVDD) is a common musculoskeletal disease affecting about 5% of all individuals. It is characterized by lumbar disc herniation, which causes nerve root irritation, either mechanically or via inflammatory mediators, and results in radiating pain, known as sciatica. Numerous studies have been conducted to identify the
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Intervertebral Disc Disease in Dogs
Veterinary Clinics of North America - Small Animal Practice, 2010Intervertebral disc herniation is a common cause of neurologic dysfunction in dogs. This article reviews the anatomy, pathophysiology, diagnostic imaging, treatment options, and prognosis for canine cervical and thoracolumbar intervertebral disc disease.
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This article describes the functional anatomy of intervertebral discs and their relationship to the vertebrae and spinal cord. The pathologic events and clinical complications of intervertebral disc disease are described. A discussion of proper staging of disc disease and appropriate conservative management of degenerative disc disease is included.
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