Results 1 to 10 of about 1,040,463 (288)

Necrostatin-1 Alleviates Diffuse Pulmonary Haemorrhage by Preventing the Release of NETs via Inhibiting NE/GSDMD Activation in Murine Lupus

Journal of Immunology Research, 2023
Diffuse alveolar haemorrhage (DAH) is a rapidly developing condition owing to a lack of effective treatment and resulting in a high mortality rate in systemic lupus erythematosus (SLE).
Xinai Han, Xiaoming Zhang, Rui Song, Shiqi Li, Shujing Zou, Quanguang Tan, Tianyang Liu, Shugeng Luo, Zhe Wu, Hongyu Jie, Jinhong Wang   +10 more
doaj   +1 more source

Comparison of category and letter fluency tasks through automated analysis

Frontiers in Psychology, 2023
IntroductionCategory and letter fluency tasks are commonly used neuropsychological tasks to evaluate lexical retrieval.MethodsThis study used validated automated methods, which allow for more expansive investigation, to analyze speech production of both ...
Carmen Gonzalez-Recober, Naomi Nevler, Sanjana Shellikeri, Katheryn A. Q. Cousins, Emma Rhodes, Mark Liberman, Murray Grossman, David Irwin, Sunghye Cho   +8 more
doaj   +1 more source

Augmenting MNK1/2 activation by c-FMS proteolysis promotes osteoclastogenesis and arthritic bone erosion

Bone Research, 2021
Osteoclasts are bone-resorbing cells that play an essential role in homeostatic bone remodeling and pathological bone erosion. Macrophage colony stimulating factor (M-CSF) is abundant in rheumatoid arthritis (RA).
Se Hwan Mun, Seyeon Bae, Steven Zeng, Brian Oh, Carmen Chai, Matthew Jundong Kim, Haemin Kim, George Kalliolias, Chitra Lekha Dahia, Younseo Oh, Tae-Hwan Kim, Jong Dae Ji, Kyung-Hyun Park-Min   +12 more
doaj   +1 more source

MEF2C regulates osteoclastogenesis and pathologic bone resorption via c-FOS

Bone Research, 2021
Osteoporosis is a metabolic bone disease with dysregulated coupling between bone resorption and bone formation, which results in decreased bone mineral density.
Takayuki Fujii, Koichi Murata, Se-Hwan Mun, Seyeon Bae, Ye Ji Lee, Tannia Pannellini, Kyuho Kang, David Oliver, Kyung-Hyun Park-Min, Lionel B. Ivashkiv   +9 more
doaj   +1 more source

Social and leisure activity are associated with attenuated cortical loss in behavioral variant frontotemporal degeneration

NeuroImage: Clinical, 2021
Behavioral variant frontotemporal degeneration (bvFTD) is clinically characterized by progressive decline in social and executive domains. Previous work suggests that early lifestyle factors such as education and occupational attainment may relate to ...
Nikolas G. Kinney, Jessica Bove, Jeffrey S. Phillips, Katheryn A.Q Cousins, Christopher A. Olm, Daniel G. Wakeman, Corey T. McMillan, Lauren Massimo   +7 more
doaj   +1 more source

Morphometric analyses of the visual pathways in macular degeneration [PDF]

, 2014
Introduction. Macular degeneration (MD) causes central visual field loss. When field defects occur in both eyes and overlap, parts of the visual pathways are no longer stimulated.
Baseler, Heidi A., Cornelissen, Frans W., Gouws, Andre, Greenlee, Mark W., Hernowo, Aditya T., Hooymans, Johanna M. M., Morland, Antony B., Plank, Tina, Prins, Doety   +8 more
core   +5 more sources

Caffeine Inhibits Oxidative Stress- and Low Dose Endotoxemia-Induced Senescence—Role of Thioredoxin-1

Antioxidants, 2023
The maintenance of Thioredoxin-1 (Trx-1) levels, and thus of cellular redox homeostasis, is vital for endothelial cells (ECs) to prevent senescence induction.
Dennis Merk, Jan Greulich, Annika Vierkant, Fiona Cox, Olaf Eckermann, Florian von Ameln, Nadine Dyballa-Rukes, Joachim Altschmied, Niloofar Ale-Agha, Philipp Jakobs, Judith Haendeler   +10 more
doaj   +1 more source

Automated Analysis of Digitized Letter Fluency Data

Frontiers in Psychology, 2021
The letter-guided naming fluency task is a measure of an individual’s executive function and working memory. This study employed a novel, automated, quantifiable, and reproducible method to investigate how language characteristics of words produced ...
Sunghye Cho, Naomi Nevler, Natalia Parjane, Christopher Cieri, Mark Liberman, Murray Grossman, Katheryn A. Q. Cousins   +6 more
doaj   +1 more source

Processing ambiguity in a linguistic context:Decision-making difficulties in non-aphasic patients with behavioral variant Frontotemporal Degeneration

Frontiers in Human Neuroscience, 2015
Some extent of ambiguity is ubiquitous in every day conversations. For example, words have multiple meaning and very common pronouns, like he and she (anaphoric pronouns), have little meaning on their own and refer to a noun that has been previously ...
Nicola eSpotorno, Meghan eHealey, Corey T. McMillan, Katya eRascovsky, David J Irwin, Robin eClark, Murray eGrossman   +6 more
doaj   +1 more source

Permissive role for mGlu1 metabotropic glutamate receptors in excitotoxic retinal degeneration [PDF]

, 2017
Neuroprotection is an unmet need in eye disorders characterized by retinal ganglion cell (RGC) death, such as prematurity-induced retinal degeneration, glaucoma, and age-related macular degeneration.
Battaglia, Giuseppe, Beneventano, Martina, Bruno, Valeria, Bucci, Domenico, Di Pietro, Paola, Liberatore, Francesca, Madonna, Michele, Mascio, Giada, Nicoletti, Ferdinando, Puliti, Alda Maria, Romano, Maria Rosaria   +10 more
core   +1 more source