Results 21 to 30 of about 696,209 (319)

Spheroidal Degeneration in Two Siblings: Clinical and Histopathological Features [PDF]

, 2021
Spheroidal corneal degeneration is predominantly seen in advanced age and hereditary predisposition to this disorder is very rare. This report describes the occurrence of bilateral band-shaped spheroidal corneal degeneration in two ...
Isikci, Ozlem Tanas, Özlem Tanas Işıkcı, MOCAN, MEHMET CEM, YABANOĞLU, DEMET, Demet Yabanoğlu, Mehmet Cem Mocan, Figen Söylemezoğlu, Mehmet Orhan, Murat İrkeç, Orhan, Mehmet, Irkec, Murat, Soylemezoglu, Figen   +11 more
core   +1 more source

Dual stimulus responsive borosilicate glass (BSG) scaffolds promote diabetic alveolar bone defectsrepair by modulating macrophage phenotype

Bioactive Materials, 2023
The regeneration of alveolar bone is still clinical challenge, particularly accompanied with diabetes, causing metabolic disorder with a protracted low-grade inflammatory phenotype.
Pengfei Tian, Limin Zhao, Jua Kim, Xian Li, Chunyu Liu, Xu Cui, Tao Liang, Yunbo Du, Xiehui Chen, Haobo Pan   +9 more
doaj   +1 more source

The estimated prevalence and incidence of late stage age related macular degeneration in the UK [PDF]

, 2012
BACKGROUND: UK estimates of age related macular degeneration (AMD) occurrence vary. AIMS: To estimate prevalence, number and incidence of AMD by type in the UK population aged ≥50 years.
Fletcher, AE, Owen, CG, Rudnicka, AR, Fletcher, Astrid E, Rudnicka, Alicja R, Jarrar, Z, Cook, DG, Wormald, Richard, Wormald, R, Owen, Christopher G, Jarrar, Zakariya, Cook, Derek G   +11 more
core   +1 more source

AMPK Signaling in Energy Control, Cartilage Biology, and Osteoarthritis

Frontiers in Cell and Developmental Biology, 2021
The adenosine monophosphate (AMP)–activated protein kinase (AMPK) was initially identified as an enzyme acting as an “energy sensor” in maintaining energy homeostasis via serine/threonine phosphorylation when low cellular adenosine triphosphate (ATP ...
Dan Yi, Dan Yi, Huan Yu, Huan Yu, Ke Lu, Ke Lu, Changshun Ruan, Changhai Ding, Changhai Ding, Liping Tong, Xiaoli Zhao, Di Chen, Di Chen   +12 more
doaj   +1 more source

Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models

Nature Communications, 2018
The human TNFAIP3 gene, which encodes for A20, is associated with autoimmune diseases. Here, the authors use BAC transgenics combined with CRISPR- and recombineering-mediated genome editing to dissect in vivo and in primary immune cells, the role of ...
Upneet K. Sokhi, Mark P. Liber, Laura Frye, Sungho Park, Kyuho Kang, Tania Pannellini, Baohong Zhao, Rada Norinsky, Lionel B. Ivashkiv, Shiaoching Gong   +9 more
doaj   +1 more source

Genius and Degeneration [PDF]

The Journal of Nervous and Mental Disease, 1897
n ...
openaire   +2 more sources

The degenerate distributive complex is degenerate [PDF]

European Journal of Mathematics, 2016
19 pages. 2nd version: the proof of Lemma A.8 is simplified.
Przytycki, Józef H., Putyra, Krzysztof K.   +1 more
openaire   +4 more sources

Prevalence of age-related macular degeneration in Nakuru, Kenya: a cross-sectional population-based study. [PDF]

, 2013
BACKGROUND: Diseases of the posterior segment of the eye, including age-related macular degeneration (AMD), have recently been recognised as the leading or second leading cause of blindness in several African countries.
Peto, Tunde; id_orcid, Bastawrous, Andrew, Andrew Bastawrous, Foster, Allen, Kuper Hannah, Allen Foster, Tunde Peto, Hannah Kuper, Tunde Peto (295260), Leung Irene, Irene Leung (336330), Leung, Irene, Wanjiku Mathenge (336328), Bastawrous Andrew, Andrew Bastawrous (336329), Peto Tunde, Hannah Kuper (25751), Wanjiku Mathenge, Allen Foster (94749), Peto, Tunde, Kuper, Hannah, Mathenge Wanjiku, Irene Leung, Mathenge, Wanjiku, Foster Allen   +24 more
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A Degenerate ParaHox Gene Cluster in a Degenerate Vertebrate [PDF]

Molecular Biology and Evolution, 2007
The ParaHox genes consist of 3 homeobox gene families, Gsx, Xlox, and Cdx, all of which have fundamental roles in development. Xlox (known as IPF1 or PDX1 in vertebrates), for example, is crucial for development of the vertebrate pancreas and is also involved in regulation of insulin expression.
Furlong, R., Younger, R., Kasahara, M., Reinhardt, R., Thorndyke, M., Holland, P.   +5 more
openaire   +3 more sources

THE STIGMATA OF DEGENERATION [PDF]

American Journal of Psychiatry, 1898
In pathology, degeneration means the substitution of a tissue by some other regarded as less highly organized, less complex in structure, of inferior physiological rank, or less suited for the performance of the original function. The same definition may apply equally well in human ontogeny, where we can regard a normal man as possessing a certain ...
openaire   +1 more source