Results 21 to 30 of about 759,258 (311)

Delusions in frontotemporal lobar degeneration [PDF]

open access: yes, 2009
We assessed the significance and nature of delusions in frontotemporal lobar degeneration (FTLD), an important cause of young-onset dementia with prominent neuropsychiatric features that remain incompletely characterised.
Nick C. Fox   +14 more
core   +2 more sources

Modelling the Genetic Risk in Age-Related Macular Degeneration [PDF]

open access: yes, 2012
Late-stage age-related macular degeneration (AMD) is a common sight-threatening disease of the central retina affecting approximately 1 in 30 Caucasians.
Weber, Bernhard H. F.   +29 more
core   +1 more source

Patterns of Microglial Cell Activation in Frontotemporal Lobar Degeneration [PDF]

open access: yes, 2013
AIMS: Pathological heterogeneity within patients with Frontotemporal lobar degeneration (FTLD) in general precludes the accurate assignment of diagnostic subtype in life.
Pickering-Brown, Stuart   +10 more
core   +1 more source

Intervertebral disc degeneration in dogs [PDF]

open access: yes, 2010
Back pain is common in both dogs and humans, and is often associated with intervertebral disc (IVD) degeneration. The IVDs are essential structures of the spine and degeneration can ultimately result in diseases such as IVD herniation or spinal ...
Bergknut, Niklas
core   +4 more sources

The estimated prevalence and incidence of late stage age related macular degeneration in the UK [PDF]

open access: yes, 2012
BACKGROUND: UK estimates of age related macular degeneration (AMD) occurrence vary. AIMS: To estimate prevalence, number and incidence of AMD by type in the UK population aged ≥50 years.
Fletcher, AE   +11 more
core   +1 more source

Long-term visual and microperimetry outcomes following autologous retinal pigment epithelium choroid graft for neovascular age-related macular degeneration [PDF]

open access: yes, 2009
To describe the 2- to 4-year visual and microperimetry outcomes of autologous retinal pigment epithelium (RPE)-choroid graft in patients with neovascular age-related macular degeneration (AMD).In this retrospective cohort study, 12 patients with ...
Coffey, PJ   +9 more
core   +1 more source

Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models

open access: yesNature Communications, 2018
The human TNFAIP3 gene, which encodes for A20, is associated with autoimmune diseases. Here, the authors use BAC transgenics combined with CRISPR- and recombineering-mediated genome editing to dissect in vivo and in primary immune cells, the role of ...
Upneet K. Sokhi   +9 more
doaj   +1 more source

A Population-Based Ultra-Widefield Digital Image Grading Study for Age-Related Macular Degeneration-Like Lesions at the Peripheral Retina. [PDF]

open access: yes, 2015
Our understanding of the relevance of peripheral retinal abnormalities to disease in general and in age-related macular degeneration (AMD) in particular is limited by the lack of detailed peripheral imaging studies.
Lengyel, Imre   +13 more
core   +1 more source

AMPK Signaling in Energy Control, Cartilage Biology, and Osteoarthritis

open access: yesFrontiers in Cell and Developmental Biology, 2021
The adenosine monophosphate (AMP)–activated protein kinase (AMPK) was initially identified as an enzyme acting as an “energy sensor” in maintaining energy homeostasis via serine/threonine phosphorylation when low cellular adenosine triphosphate (ATP ...
Dan Yi   +12 more
doaj   +1 more source

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