Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration
Cell Proliferation, EarlyView.Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen +9 more
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The impact of compressive force magnitude on the in vitro neutral zone range and passive stiffness during a flexion–extension range of motion test [PDF]
, 2015 Noguchi, M., Gooyers, C. E., Holmes, M. W. R., & Callaghan, J. P. (2015). The impact of compressive force magnitude on the in vitro neutral zone range and passive stiffness during a flexion-extension range of motion test. Cogent Engineering, 2(1). https:/
Callaghan, Jack P. +3 more
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Equine Veterinary Education, EarlyView.Summary A 3‐year‐old Poitou donkey was referred for a computed tomography (CT) examination of the cervical spine due to acute deterioration of spinal ataxia. Neurological assessment revealed restricted neck mobility, hypermetria and circumduction of all limbs, indicating a grade 2 out of 5 ataxia.
M. Mikic +3 more
wiley +1 more source
Uneven intervertebral motion sharing is related to disc degeneration and is greater in patients with chronic, non-specific low back pain. An in-vivo, cross-sectional cohort comparison of intervertebral dynamics using quantitative fluoroscopy. [PDF]
, 2018 Purpose: Evidence of intervertebral mechanical markers in chronic, non-specific low back pain (CNSLBP) is lacking. This research used dynamic fluoroscopic studies to compare intervertebral angular motion sharing inequality and variability (MSI and MSV ...
Breen, Alan C., Breen, Alexander C.
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An overview of reliable and representative DVC measurements for musculoskeletal tissues
Journal of Microscopy, EarlyView.Abstract Musculoskeletal tissues present complex hierarchical structures and mechanical heterogeneity across multiple length scales, making them difficult to characterise accurately. Digital volume correlation (DVC) is a non‐destructive imaging technique that enables quantification of internal 3D strain fields under realistic loading conditions ...
Gianluca Tozzi, Enrico Dall'Ara
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Nano Biomedicine and Engineering, 2017 Orthopedic fixation devices are widely used in treatment of spinal diseases. It is expected that application of dynamic stabilization confers valuable movement possibility besides its main role of load bearing.
Samir Zahaf, Said Kebdani
doaj +1 more source
Characterisation of spinal ligaments in the embryonic chick
Journal of Anatomy, EarlyView.Use of the embryonic chick provides an opportunity to examine the maturation of spinal ligaments during development, to inform anatomical defects in the spine. Abstract Ligaments are important connective tissues within the musculoskeletal system that connect bone to bone and provide support and stability.
Sarah Hennigan +2 more
wiley +1 more source
Histologic Evaluation of the Efficacy of rhBMP-2 Compared With Autograft Bone in Sheep Spinal Anterior Interbody Fusion [PDF]
, 2002 Study Design. The sheep anterior lumbar spinal fusion model was used to study the efficacy of recombinant human bone morphogenetic protein-2 (rhBMP-2)–collagen composite in comparison with autograft to enhance spinal interbody fusion.
Diwan, Ashish +6 more
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The effects of physiological biomechanical loading on intradiscal pressure and annulus Stress in lumbar spine: a finite element analysis [PDF]
, 2017 The present study was conducted to examine the effects of body weight on intradiscal pressure (IDP) and annulus stress of intervertebral discs at lumbar spine.
Kadir, M. R. A. +4 more
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Journal of Small Animal Practice, EarlyView.Objectives The purpose of this study was to determine clinical and neurological data on the stabilisation of thoracolumbar region fractures or luxations in cats with the polyaxial screw rod system. Materials and Methods The study included 16 cats with thoracic and/or lumbar fractures, luxations and/or instability.
M. N. Çetin, Y. S. Şirin
wiley +1 more source